Sona Nanotech

Sona Nanotech: Leveraging Nanotechnology in Colorectal Cancer Therapy


Sona Nanotech (CSE:SONA, OTCQB:SNANF) advances nanotechnology medicine through its proprietary gold nanorods that promise to change the face of cancer therapy. Sona Nanotech's platform technology leverages uniquely biocompatible gold nanorods (GNRs). Biocompatibility is key to the application of nanotechnology in medicine.

For the past several years, Sona has been working hard to develop and operationalize its biocompatible nanoparticle technology for use in targeted cancer therapy. The company is also developing a targeted cancer therapy, leveraging its proprietary Targeted Hyperthermia Therapy (THT) to directly treat cancer cells.

Sona's Platform Technology

Sona's GNRs are rod-shaped nanoparticles made of gold and measuring from 10 to 100 nanometers in length. Produced by chemical synthesis, they directly address many of the current limitations of medical nanoparticle technologies. In addition to making them well-suited for cancer treatment, this also unlocks their potential for use in in-vivo medical applications.

Company Highlights

  • Canadian nanotechnology company, Sona Nanotech has developed an incredibly promising new technology that leverages uniquely biocompatible gold nanorods.
  • The company also plays a key role in the advancement of photothermal medical therapies, particularly enabled by the company's acquisition of Siva Therapeutics.
  • This acquisition has allowed Sona to advance the development of Targeted Hypothermia Therapy, addressing many of the risks with current cancer treatments — particularly the damage they can cause to other tissues.
  • THT has already proven effective in reducing tumors in small animal studies. Sona's initial target for the technology will be colorectal cancer.
  • Rapid diagnostic tests represent the company's other strategic area of focus, including bovine tuberculosis detection and concussion screening.
  • Future applications for Sona's technology could include:
    • Targeted drug delivery
    • Photothermal cosmetic therapy
    • Cell imaging
    • Additional proprietary testing solutions supported by third-party test development services.
  • The company's leadership and board of directors comprise experienced professionals from across the healthcare and biotechnology sectors.
  • Sona has a clear roadmap to commercialization of its treatment methodology, starting with a near-term catalyst in large animal studies before moving to a human pilot. It also expects a De Novo pathway for medical devices.

This Sona Nanotech is part of a paid investor education campaign.*

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Sona Nanotech

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Sona Nanotech Provides Interim Results of Dalhousie Efficacy Study

Sona Nanotech Provides Interim Results of Dalhousie Efficacy Study

Sona Nanotech Inc. (CSE: SONA) (OTCQB: SNANF) (the "Company" or "Sona") is pleased to announce further positive interim results from its study with The Giacomantonio Immuno-Oncology Research Group at Dalhousie University (the "Study"). The Company was provided with data from the Study that indicates the response in a pre-clinical triple negative breast cancer model treated with the combination of Sona's targeted hyperthermia therapy ("THT") and interleukin-2 ("IL-2"), a standard immunotherapy, is statistically significantly superior to results observed from treatment with either agent individually or the control group. This second phase of the Study has documented that, in a cohort of six animals, 66 of treated triple negative breast cancer, the most aggressive and therapy resistant form, mouse tumors bearing gold nanorods and IL-2 responded to the combination therapy, resulting in a flattening of the tumor growth curves, as shown in the below graph. The generation of hyperthermia involved exposing tumors previously injected intratumorally with Sona's gold nanorods and IL-2 to a single dose of near infrared light.

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Sona Nanotech Secures Grant Funding to Support Intellectual Property Strategy and Development

Sona Nanotech Secures Grant Funding to Support Intellectual Property Strategy and Development

Sona Nanotech Inc. (CSE: SONA) (OTCQB: SNANF) (the "Company" or "Sona") announces that it has been approved for funding totaling approximately $40,000 to support the development of its intellectual property portfolio.

The Company is receiving advisory services and up to $24,894 in funding from the National Research Council of Canada Industrial Research Assistance Program ("NRC IRAP") IP Assist program to support the development of an intellectual property strategy for Sona's proprietary gold nanorods for novel targeted drug delivery concepts with a view to securing new patents.

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Sona Nanotech Updates on Dalhousie Efficacy Study and New NCL Results

Sona Nanotech Updates on Dalhousie Efficacy Study and New NCL Results

Sona Nanotech Inc. (CSE: SONA) (OTCQB: SNANF) (the "Company" or "Sona") announces positive interim results from its study with The Giacomantonio Immuno-Oncology Research Group at Dalhousie University (the "Study"). An update received by the Company indicates that all tumors treated within the Study to date with a single Targeted Hyperthermia Therapy ("THT") treatment shrunk within the first 24 hours, with an average reduction in size of 80% compared to matched controls.

Study Principal Investigator, Dr. Carman Giacomantonio, comments, "Our initial assessment documented that in cohorts of seven animals, 7/7 of treated triple negative breast cancer mouse tumors bearing gold nanorods responded with an average reduction in tumor volume of 80% following a single treatment with near infrared light in comparison with untreated 'control' tumors. Interestingly, in all cases we observed responses (tumor shrinkage) in distant, untreated tumors supporting the hypothesis that our observations are consistent with systemic immunogenic responses. This observation will be a significant focus of our research going forward. While we are encouraged by these initial results, there is still significant work to be completed. The studies are designed to enable and identify statistical significance which will be achieved with the completion of the full Study."

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Sona Nanotech Announces Filing of Provisional Patent Application

Sona Nanotech Announces Filing of Provisional Patent Application

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A prototype of Sona's medical laser was engineered in conjunction with Minnetronix Medical to apply non-thermal, 860 nanometer wavelength high intensity infrared laser light. The device has been designed for use with Sona's patented/patent pending biocompatible gold nanorods which efficiently convert the non-thermal light energy into heat. The device has controls to regulate the intensity and duration of the light exposure and to permit a user to monitor and control the temperature generated in tissue. The device is currently being used for the Company's ongoing pre-clinical efficacy study of its Targeted Hyperthermia Therapy cancer treatment at Dalhousie University.

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Sona Nanotech Grants Options

Sona Nanotech Grants Options

Sona Nanotech Inc. (CSE: SONA), (OTCQB: SNANF) (the "Company" or "Sona") announces that that it has granted 1,195,000 incentive stock options under the Company's Stock Option Plan ("Option Plan"), of which 810,000 have been granted to a Directors and Officers. Each option is exercisable into one common share at a price of $0.31 per share and will vest at the rate of 25% every six months. The options will expire five years from the date of grant. All other terms and conditions of the options are in accordance with the terms of the Company's Stock Option Plan.

Contact:
David Regan, CEO
+1-902-536-1932
david@sonanano.com

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Nuvation Bio Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update

Nuvation Bio Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update

Determined maximum tolerated dose (MTD) in Phase 1 monotherapy study of NUV-868; Phase 1b studies of NUV-868 in combination with olaparib or enzalutamide remain ongoing

Received U.S. Food and Drug Administration (FDA) clearance of Investigational New Drug (IND) application for NUV-1511, the first clinical candidate from our novel drug-drug conjugate (DDC) platform

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Nuvation Bio Announces Appointment of Dr. Robert Mashal to its Board of Directors

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Nuvation Bio Inc. (NYSE: NUVB), a biopharmaceutical company tackling some of the greatest unmet needs in oncology by developing differentiated and novel therapeutic candidates, today announced the appointment of Robert Mashal, M.D. to its Board of Directors.

"We are delighted to have Dr. Mashal join our Board of Directors," said David Hung, M.D., Founder, President, and Chief Executive Officer of Nuvation Bio. "Robert is a seasoned biotech industry veteran and his experience as an investor, operator, and medical oncologist will provide us with valuable insights. We look forward to working with Robert to advance Nuvation's pipeline."

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Company anticipates initiating a Phase 1/2 clinical study of NUV-1511 in 1H 2024

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NanoXplore Receives TSX Approval for Normal Course Issuer Bid

NanoXplore Inc. (TSX: GRA) ("NanoXplore" or the "Corporation") is pleased to announce that the Toronto Stock Exchange (TSX) has approved the Corporation's request to adopt a normal course issuer bid (NCIB) program, through which NanoXplore may purchase, for cancellation, up to 5,936,205 common shares or approximately 5% of the public float (consisting of 118,724,119 common shares as of November 22, 2023, out of the 169,378,431 common shares issued and outstanding). The Corporation may purchase shares under the NCIB over a period of twelve months commencing on December 1, 2023 and ending November 30, 2024, when the bid expires. NCIB purchases are through the facilities of the TSX and certain Canadian Alternative Trading Systems and the price for any repurchased shares will be the prevailing market price at the time of the acquisition.

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NanoXplore Unveils a Large-Scale Dry Process for Manufacturing of Graphene: An Improvement for Cost Competitiveness and Scalability

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NanoXplore Reports Results for its Q1-2024

NanoXplore Inc. ("NanoXplore" or "the Corporation") (TSX: GRA and OTCQX: NNXPF), a world-leading graphene company, reported today financial results for the three-month period ended September 30, 2023.

All amounts in this press release are in Canadian dollars, unless otherwise stated.

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