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Axsome Therapeutics (NASDAQ:AXSM) has received a new US patent concerning intellectual property protection for AXS-02 for the treatment of complex regional pain syndrome.
Axsome Therapeutics (NASDAQ:AXSM) has received a new US patent concerning intellectual property protection for AXS-02 for the treatment of complex regional pain syndrome.
As quoted in the press release:
The patented claims cover uses of oral zoledronic acid, the active moiety in AXS-02, for the treatment of CRPS. Another patent covering uses of oral zoledronic acid for the treatment of CRPS (U.S. Patent No. 9,216,168) was issued in December 2015 and provides additional protection. The terms of these issued patents extend into 2033 and 2034, respectively. These patents are part of a portfolio of 19 issued patents covering AXS-02, other bisphosphonates or other osteoclast inhibitors. AXS-02 is a potent osteoclast inhibitor developed by Axsome as an oral, targeted, non-opioid, potentially first-in-class therapeutic for chronic pain, including pain associated with CRPS.
CRPS is a debilitating condition characterized by severe, continuous, burning or throbbing pain in a limb. The excessive pain is accompanied by changes in skin color, temperature and/or swelling. It is considered to be one of the most painful conditions, results in loss of physical function, and can lead to significant and sometimes permanent disability. There is currently no medication approved for the treatment of CRPS.