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    2 Biggest Medical Device ETFs in 2025

    Melissa Pistilli
    Feb. 17, 2025 01:15PM PST

    Medical device ETFs offer diversification, an important feature in the medical device market, as they hold a basket of equities.

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    PopTika / Shutterstock

    Exchange-traded funds (ETFs) are a popular investment strategy, and generally contain a variety of publicly traded companies under one stock symbol, often with a focus on a specific sector.

    Depending on the ETF, investors may be able to track up-and-coming companies, get exposure to top firms or a mix of both. Aside from stocks, some ETFs also track commodities or bonds.

    In the healthcare industry, medical device ETFs bring together companies that go to great lengths to develop pharmaceutical-based technology that can improve the lives of patients.


    To help investors make decisions when it comes to medical device ETFs, here the Investing News Network provides a brief breakdown of what ETFs are and a look at the medical device ETFs you can invest in.

    What is an exchange-traded fund?

    Exchange-traded funds, or ETFs, hold a basket of equities, often focused on a theme or niche. ETFs are appealing because they give investors the ability to hone in on a specific market area without investing in individual companies. While they are similar to mutual funds, ETFs trade on stock exchanges in the same way stocks do.

    Put simply, ETFs reduce the risk of investing by providing access to a larger pool of companies — they let investors pick an area that interests them and suffer less financially if one company under the ETF’s umbrella underperforms. In this way, ETFs allow investors to enter the market confidently and hopefully enjoy long-term capital gains.

    Like many areas of the life science space, the medical device sector can be volatile, making ETFs particularly appealing. For example, if a company in a medical device ETF fails a clinical trial or receives negative feedback from the US Food and Drug Administration, ETF investors will largely be protected from any share price drop the stock might have.

    On the other hand, if a company in a medical device ETF sees a major gain, that increase will also be muted for ETF investors. That's why some investors prefer to take their chances by adding individual stocks to their portfolios.

    Medical device ETFs to consider

    Investors keen on medical device ETFs only have three choices, according to ETFdb.com.

    Here’s a brief look at the two biggest medical device ETFs available. The third ETF, the First Trust Indxx Medical Devices ETF (BATS:MDEV), is much smaller, with total assets of only US$2.16 million.

    1. iShares US Medical Devices ETF (ARCA:IHI)

    Company Profile

    Total assets: US$5.1 billion

    The iShares US Medical Devices ETF was launched in 2006 and tracked 50 holdings as of February 11, 2025. This iShares ETF has more than US$5.1 billion in assets under management and its top three constituents by weight are:

    • Abbott Laboratories (NYSE:ABT): Abbott Laboratories’ medical devices are geared towards vascular disease, diabetes and vision care.
    • Intuitive Surgical (NASDAQ:ISRG): This medical device firm is the maker of the da Vinci surgical and Ion endoluminal systems. These robotic products are designed to improve clinical outcomes for patients through minimally invasive surgery.
    • Boston Scientific (NYSE:BSX): Boston Scientific's device portfolio is extensive. Its areas of focus include gastroenterology, cardiac and vascular surgery, neurological and orthopedic surgeries, and urology.

    2. SPDR S&P Health Care Equipment ETF (ARCA:XHE)

    Company Profile

    Total assets: US$208.99 million

    Formed on January 26, 2011, the SPDR S&P Health Care Equipment ETF tracked 66 holdings as of February 11, 2025. This SPDR ETF has more than US$208 million in assets under management and some of its top holdings are:

    • Inari Medical (NASDAQ:NARI): Headquartered in California, Inari Medical developed the first mechanical thrombectomy system to receive FDA 510(k) clearance for the treatment of pulmonary embolism.
    • AtriCure (NASDAQ:ATRC): Another venous-focused medical device company, AtriCure developed the first medical device to receive FDA approval for the treatment of persistent atrial fibrillation.
    • iRhythm Technologies (NASDAQ:IRTC): Medical device firm iRhythym Technologies combines wearable biosensors and cloud-based data analytics with its proprietary algorithms to produce clinical actionable information.

    This is an updated version of an article originally published by the Investing News Network in 2016.

    Don’t forget to follow us @INN_LifeScience for real-time news updates!

    Securities Disclosure: I, Melissa Pistilli, hold no direct investment interest in any company mentioned in this article.

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    The Conversation (2)
    Elias Azrak
    Elias Azrak
    05 Jun, 2017
    There is a third ETF that you might consider adding to your list: "IMED" PureFunds ETFx HealthTech ETF
    0 Replies Hide replies
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    Elias Azrak
    Elias Azrak
    05 Jun, 2017
    There is a third ETF that you might consider adding to your list: "IMED" PureFunds ETFx HealthTech ETF
    0 Replies Hide replies
    Show More Replies

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    Melissa Pistilli

    Melissa Pistilli

    Educational Content Specialist

    Melissa Pistilli has been reporting on the markets and educating investors since 2006. She has covered a wide variety of industries in the investment space including mining, cannabis, tech and pharmaceuticals. She helps to educate investors about opportunities in a variety of growth markets. Melissa holds a bachelor's degree in English education as well as a master's degree in the teaching of writing, both from Humboldt State University, California.

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    Melissa Pistilli
    Melissa Pistilli

    Educational Content Specialist

    Melissa Pistilli has been reporting on the markets and educating investors since 2006. She has covered a wide variety of industries in the investment space including mining, cannabis, tech and pharmaceuticals. She helps to educate investors about opportunities in a variety of growth markets. Melissa holds a bachelor's degree in English education as well as a master's degree in the teaching of writing, both from Humboldt State University, California.

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