Actinium Pharmaceuticals to obtain patent for key drug ingredient Actinium-225

Actinium Pharmaceuticals (NYSE MKT: ATNM) has been allowed to patent the way it generates Actinium-225, the radioisotope used in Actinium’s Actimab-A, Actimab-M both drug candidates and as the company’s alpha particle immunotherapy technology platform.
As quoted in the press release:

This patent is expected to expire in July of 2030.
Sandesh Seth, Actinium’s Executive Chairman said, “Actinium-225 is an excellent isotope for medical applications given its half-life, potency, safety profile and relatively ease of handling. As a result, it is an important aspect of Actinium’s Actimab-A and Actimab-M programs and alpha particle immunotherapy technology (APIT) platform. We welcome this addition to our intellectual property portfolio, which now consists of more than 60 patents. We will continue to invest in our intellectual property portfolio to further enhance our position in the use of alpha particles to enhance outcomes for patients.”
The claims of this patent are for a method for producing actinium-225 radioconjugates, the method comprising the steps of: a) conjugating a chelating agents to a biological molecule in a conjugations reaction mixture to generate a conjugated biological molecule, b) purifying the reaction mixture so as to remove unconjugated chelating agents, and c) chelating one or more actinium-225 radionuclides with the conjugated biological molecule in a chelation reaction mixture to generate an actinium-225 radioconjugate.
Sandesh Seth, Executive Chairman of Actinium Pharmaceuticals said, “Steve’s hiring represents another significant step in Actinium’s growth and one that I am most excited about. Steve brings to Actinium a significant amount of knowledge and experience specific to hematology and also has deep relationships that he curated in his 30 years in this field. I look forward to working with Steve and the rest of the Actinium team in building a great company that is focused on improving outcomes for patients.”
 
 

Click here for full press release.