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ContraVir Pharmaceuticals Completes Renal Impairment Study with TXL™
Feb. 06, 2018 08:26AM PST
Pharmaceutical InvestingContraVir Pharmaceuticals (NASDAQ:CTRV), a biopharmaceutical company focused on the development and commercialization of targeted antiviral therapies, announced today the results of a Phase 1 study with TXL™ assessing the safety, pharmacokinetics and tolerability of TXL™ in patients with severe renal impairment. As quoted in the press release: Importantly, the data showed that the blood concentrations …
ContraVir Pharmaceuticals (NASDAQ:CTRV), a biopharmaceutical company focused on the development and commercialization of targeted antiviral therapies, announced today the results of a Phase 1 study with TXL™ assessing the safety, pharmacokinetics and tolerability of TXL™ in patients with severe renal impairment.
As quoted in the press release:
Importantly, the data showed that the blood concentrations of tenofovir (TFV) in severely renally-impaired subjects receiving 50 mg of TXL™ were similar to the TFV exposure levels observed after dosing of Viread® 300 mg, the current standard of care. These findings indicate that dosing strength adjustments of TXL™ is not warranted in patients with compromised renal function.
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