- AustraliaNorth AmericaWorld
Investing News NetworkYour trusted source for investing success
- Lithium Outlook
- Oil and Gas Outlook
- Gold Outlook Report
- Uranium Outlook
- Rare Earths Outlook
- All Outlook Reports
- Top Generative AI Stocks
- Top EV Stocks
- Biggest AI Companies
- Biggest Blockchain Stocks
- Biggest Cryptocurrency-mining Stocks
- Biggest Cybersecurity Companies
- Biggest Robotics Companies
- Biggest Social Media Companies
- Biggest Technology ETFs
- Artificial Intellgience ETFs
- Robotics ETFs
- Canadian Cryptocurrency ETFs
- Artificial Intelligence Outlook
- EV Outlook
- Cleantech Outlook
- Crypto Outlook
- Tech Outlook
- All Market Outlook Reports
- Cannabis Weekly Round-Up
- Top Alzheimer's Treatment Stocks
- Top Biotech Stocks
- Top Plant-based Food Stocks
- Biggest Cannabis Stocks
- Biggest Pharma Stocks
- Longevity Stocks to Watch
- Psychedelics Stocks to Watch
- Top Cobalt Stocks
- Small Biotech ETFs to Watch
- Top Life Science ETFs
- Biggest Pharmaceutical ETFs
- Life Science Outlook
- Biotech Outlook
- Cannabis Outlook
- Pharma Outlook
- Psychedelics Outlook
- All Market Outlook Reports
Hemispherx Announces First Participant Received Initial Dosing in Breast Cancer Clinical Trial
Hemispherx (NYSE American:HEB) has announced the active initiation of a clinical trial sponsored by Roswell Park Comprehensive Cancer Center, evaluating the company’s experimental drug Ampligen in combination with Merck’s (NYSE:MRK) Keytruda in treating metastatic triple-negative breast cancer. As quoted in the press release: The study’s first participant received initial dosing this week. The phase I …
Hemispherx (NYSE American:HEB) has announced the active initiation of a clinical trial sponsored by Roswell Park Comprehensive Cancer Center, evaluating the company’s experimental drug Ampligen in combination with Merck’s (NYSE:MRK) Keytruda in treating metastatic triple-negative breast cancer.
As quoted in the press release:
The study’s first participant received initial dosing this week. The phase I trial seeks to enroll at least six patients
Lead investigators Drs. Mateusz Opyrchal and Pawel Kalinski of Roswell Park will evaluate the impact of Ampligen-based chemokine modulation therapy when given prior to pembrolizumab in the treatment of patients with metastatic triple-negative breast cancer. Drugs used in this chemokine modulation therapy — celecoxib, recombinant interferon alfa-2b, and Ampligen — potentially work by unleashing or enhancing the cancer immune responses that already exist by either blocking inhibitory molecules or by activating stimulatory molecules. Based on past experimental and clinical data, the research team is undertaking the study to determine whether this approach can positively modify the tumor microenvironment to convert previously ‘cold’ tumors not susceptible to checkpoint blockade therapy into ‘hot’ tumors which are optimally primed for checkpoint-blockade therapies.
“We are very excited to see the first patient treated as part of this important clinical trial evaluating Ampligen in combination with pembrolizumab in patients with metastatic triple-negative breast cancer. We could not ask for better partners than the world-class team at Roswell Park Comprehensive Cancer Center, as we seek to evaluate the impact of the combined therapy on this high risk and very sick patient population,” said Hemispherx CEO Thomas K. Equels. “Our extensive work with Ampligen has led many top oncologists to conclude, including in peer reviewed medical journal articles, that Ampligen has the potential to change the tumor microenvironment. Making tumors easier targets for checkpoint blockade therapies creates an exciting new approach with the potential to significantly improve clinical outcomes for patients in multiple solid tumor cancer types.”
Latest News
Investing News Network websites or approved third-party tools use cookies. Please refer to the cookie policy for collected data, privacy and GDPR compliance. By continuing to browse the site, you agree to our use of cookies.