Can-Fite Announces Enrollment of First Patient in its Comfort Phase III Trial of Piclidenoson in Psoriasis

Can-Fite BioPharma (NYSE:CANF) (TASE:CFBI), a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today announced the first patient has been enrolled and dosed in its Phase III Comfort™ trial to evaluate its lead drug candidate, Piclidenoson (CF101), a small orally bioavailable drug for the treatment of moderate-to-severe plaque psoriasis, which makes up about 90 percent of cases.

As quoted in the press release:

The Comfort™ Phase III Psoriasis study, is designed to evaluate the efficacy and safety of daily Piclidenoson, administered orally compared to Apremilast (Otezla®) and placebo, in 407 patients with moderate-to-severe plaque psoriasis. The study will be conducted in 5 countries in Europe, Israel and Canada. The first patient has been enrolled and dosed in Israel with enrollment in Europe and Canada expected to follow shortly.

Study initiation will prompt a milestone payment of 300,000 Euro from the recently signed deal with Gebro Holding which will distribute the drug upon regulatory approval in Spain, Austria and Switzerland. According to Visiongain, the psoriasis therapeutic market is estimated to reach $11.4B in 2020.

Click here to read the full press release.