NanoSphere Health Sciences Has Received Notice of Allowance for a Patent for its Breakthrough Nanoparticle Encapsulations of NSAIDs
NanoSphere Health Sciences (CSE:NSHS) (OTC: NSHSF) has received formal Notice of Allowance from the Canadian Intellectual Property Office (CIPO) for Application 2,970,91, covering “The Method of Treating Inflammatory Disorders and Global Inflammation with Phospholipid Nanoparticle Encapsulations of NSAIDs.” NSAIDs being non-steroidal anti-inflammatory drugs, which include ibuprofen, aspirin, and naproxen among others.
This patent allowance adds to NanoSphere’s already robust IP portfolio. In 2018 NanoSphere received a master patent covering NanoSphere’s core technology, the NanoSphere Delivery System™. This groundbreaking delivery platform encapsulates a broad range of bioactive compounds in a protective membrane, transporting them rapidly and effectively into the bloodstream and cells for the most rapid and effective results.
“Nano-encapsulating NSAIDs in a stable nanoparticle structure allows for a more rapid onset of symptom relief, longer lasting activity, greater therapeutic activity from a smaller dose and potential reduction of dangerous side effects,’ said Chief Science Officer Richard Clark Kaufman. “The current class of NSAID drugs are very effective, but they can also create an increased risk of gastrointestinal bleeding or ulcers, heart attacks, kidney disease, and liver failure,” said Kaufman. “Our research has been aimed at delivering these medicines both systemically and locally to target sites without passing through the gastrointestinal tract. By doing so we can create more effective treatments, with fewer adverse effects and enable long-term, safer use of NSAIDs.”
“The granting of the patent further establishes NanoSphere as an advanced biotech company and secures our position as the leader in advanced nanoparticle delivery,” said Robert Sutton, CEO of NanoSphere Health Sciences. “Through our research and development, we aim to be the de facto mode for NSAID delivery worldwide, which according to Allied Market Research, the market is in excess of $100 billion, with an annual growth rate of 5.9%.”
With the issuance of this patent, NanoSphere will now have long-term market exclusivity over this delivery platform for NSAIDs with patent infringement prohibited. The company will now officially launch commercial development of a platform of pharmaceutical applications for the treatment of pain and inflammation. This patent allows for nanoparticle encapsulation of NSAIDs for transdermal, intranasal and intraoral applications, providing superior advantages over traditional pain management therapies.
“This patent confirms NanoSphere’s commitment to creating a portfolio of non-opioid analgesics that can be delivered by a variety of methods. Administration of NSAIDs through oral or intravenous routes is not always convenient or even possible. Utilizing its patented delivery system, NanoSphere will make available a safe and precise alternative for NSAID delivery,” said Senior Director of NanoSphere’s NSAID program, David Theil, M.D.
On behalf of the Board
Robert Sutton, Chairman and CEO
Victor Goncalves, Executive Vice President
About NanoSphereHealth Science, Inc.
NanoSphere Health Sciences Inc., is a biotechnology firm specializing in the creation of the NanoSphere Delivery System™, a revolutionary platform using nanotechnology for the biodelivery of supplements, nutraceuticals and over-the-counter medications for the cannabis, pharmaceutical and animal health industries, and beyond. For more information on NanoSphere, please visit http://www.nanospherehealth.com.
About Evolve Formulas
Evolve Formulas, product line developed by NanoSphere Health Sciences, is the provider of the world’s first and only scientifically proven nanoparticle delivery system in cannabis. Evolve’s pioneering product, Transdermal NanoSerum™, is a fast-acting, ultra-strength transdermal formula infused with nano-encapsulated cannabis and cannabis extracts. For more information on Evolve Formulas, visit https://www.evolveformulas.com/. Follow us on Facebook, Instagram and Twitter.
The Canadian Securities Exchange does not accept responsibility for the adequacy or accuracy of this release.
Forward Looking Statement Caution
This news release includes forward looking statements that are subject to assumptions, risks and uncertainties. Statements in this news release which are not purely historical are forward looking statements, including without limitation any statements concerning the Company’s intentions, plans, estimates, expectations or beliefs regarding the future. Although the Company believes that any forward looking statements in this news release are reasonable, there can be no assurance that any such forward looking statements will prove to be accurate. The Company cautions readers that all forward looking statements, including without limitation those relating to the Company’s future operations and business prospects, are based on assumptions none of which can be assured, and are subject to certain risks and uncertainties that could cause actual events or results to differ materially from those indicated in the forward looking statements. Readers are advised to rely on their own evaluation of such risks and uncertainties and should not place undue reliance on forward looking statements. Any forward looking statements are made as of the date of this news release, and the Company assumes no obligation to update the forward looking statements, or to update the reasons why actual events or results could or do differ from those projected in the forward looking statements, whether as a result of new information, future events or otherwise.
Kate Wells NanoSphere Health Sciences (303) 324-7358 firstname.lastname@example.org
CanBud Distribution Corporation Closes 2M Second and Final Tranche of its Oversubscribed Private Placement Offering
CanBud Distribution Corporation (CSE: CBDX) (FSE: CD0) (“CanBud” or the “Corporation”) is pleased to announce that it has closed the final tranche of its oversubscribed non-brokered private placement for aggregate gross proceeds of approximately $4,730,000 (the “Offering”).
The Corporation issued a combined total of 39,409,346 units (each a “Unit“) at price of $0.12 per Unit, with each Unit comprised of one common share in the capital of the Corporation (each a “Common Share“) and one common share purchase warrant (each a “Warrant“). Each Warrant entitles the holder to purchase one additional Common Share at an exercise price of $0.22 within 24 months of the closing of the Offering (the “Warrant Term“), provided, however that if the closing price of the Common Shares on the Canadian Securities Exchange (the “CSE“) (or any such other stock exchange in Canada as the Common Shares may trade at the applicable time) is $0.25 or greater per Common Share for a period of five (5) consecutive trading days at any time after the closing date of the Offering, the Corporation may accelerate the Warrant Term such that the Warrants shall expire on the date which is 30 days following the date a press release is issued by the Corporation announcing the reduced warrant terms.
Thoughtful Brands Inc. (CSE:TBI)(FSE:1WZ1)(OTCQB:PEMTF) (the “Company” or “Thoughtful Brands) announces that the letter of intent with Franchise Cannabis Corp. (“FCC”), previously announced in January, has been terminated. The previously announced European joint venture with FCC will continue and allow the Company to launch and tailor its products to European consumer demands
In connection with termination of the merger transaction with FCC, the Company has agreed to pay FCC $100,000 in cash and to issue FCC 5,000,000 common shares of the Company at a deemed value of $0.05 per share. The common shares will be subject to a four-month-and-one-day statutory hold period in accordance with applicable securities laws.
Mergers and acquisitions (M&A) in cannabis space have helped boost the industry to new levels.
Strategic sale of non-core assets by Lobe adds non-dilutive capital and shareholder value
Lobe Sciences Ltd. (CSE: LOBE) (OTC Pink: GTSIF) (“Lobe” or the “Company”) is pleased to announce, further to its press release dated February 23, 2021, that it has completed the sale to Ionic Brands Corp. (“Ionic Brands”) of Lobe’s non-core cannabis assets relating to Washington-based Cowlitz County Cannabis Cultivation Inc. (“Cowlitz”) held by Lobe’s subsidiary vendor, Green Star Biosciences Inc. (the “Transaction”).
Seattle Area Grocery Chain Metropolitan Market to Begin Carrying KOIOS and Fit Soda on March 22, 2021
Adding to its existing presence on the west coast of the United States, all five KOIOS™ flavours and all four Fit Soda™ flavours will be carried in Metropolitan Market stores beginning on Monday, March 22, 2021. Serving the Seattle-Tacoma area (population 3.87 million), Metropolitan Market is one of five chains under its parent firm Good Food Holdings, which has a total of 51 stores in California, Oregon, and Washington State.
Koios Beverage Corp. (CSE: KBEV; OTC: KBEVF) (the “Company” or “Koios”) is pleased to announce that beginning on Monday, March 22, 2021, Koios’ entire line of canned beverage products will be sold at all locations of Metropolitan Market, an urban format supermarket chain in the Seattle-Tacoma area of Washington State. In Q1 2021, the Company announced multiple placements of its beverage products with regional grocers in markets on the west coast of the United States including Market of Choice in Oregon Jensen’s in Southern California and major natural grocery chain Sprouts Farmers Market which has a substantial west coast presence with over one third of its locations (360+ stores across 23 states) in California as well as Washington State 1 . The Company has also recently announced other developments relating to its expansion efforts being undertaken in 2021 such as an in-house beverage canning facility and distribution agreements with regional and national wholesale partners.