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Lion Biotechnologies Adds Data Presentation at ASCO Meeting
Lion Biotechnologies will present additional data from its ongoing Phase 2 study of LN-144 treating metastatic melanoma at the 2017 American Society of Clinical Oncology annual meeting.
Lion Biotechnologies (NASDAQ:LBIO) will present additional data from its ongoing Phase 2 study of LN-144 treating metastatic melanoma at the 2017 American Society of Clinical Oncology annual meeting.
As quoted in the press release:
“The data presented today demonstrate that we can manufacture TIL at our central GMP facilities and treat a patient population with a high unmet need at multiple clinical sites,” said Dr. Maria Fardis, PhD, MBA, Chief Executive Officer of Lion Biotechnologies. “These initial data show clinically-meaningful outcomes, as assessed both by ORR and DCR, in a heavily pre-treated patient group, all of which had received prior anti-PD-1 and over 80% with prior anti-CTLA-4 checkpoint inhibitors.”
This Phase 2, multicenter, three-cohort study is designed to assess the safety and efficacy of LN-144 for treatment of patients with metastatic melanoma. Cohorts one and two will now enroll up to 30 patients each and cohort three is a re-treatment cohort for a second LN-144 infusion in up to ten patients. The first two cohorts are evaluating two different manufacturing processes for LN-144. Patients in cohort one are receiving fresh, non-cryopreserved TIL and cohort two patients are receiving product manufactured through a more streamlined and rapid three-week procedure yielding a cryopreserved product.
Click here to read the full press release.
Source: www.marketwired.com
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