Multiple Myeloma Therapeutics Market Expected to Reach $4.26 Billion in 2030

FN Media Group News Commentary - Recent reports show that the Multiple myeloma Diagnostic market will continue to grow in the next several years. Multiple myeloma is a type of plasma cell cancer. Normal plasma cells are recognized as an important component of the immune system. The immune system is made up of various types of cells that work together to fight infections and other diseases. The main types of white blood cells in the immune system are lymphocytes (lymph cells) such as T-cells and B-cells. Multiple myeloma develops when these plasma cells become cancerous in nature and grow abnormally. A report from Data Bridge Market Research said that the North American multiple myeloma diagnostic market which was USD 3732.64 million in 2022, is expected to reach USD 5390.01 million by 2030, at a CAGR of 4.7% during the forecast period 2023 to 2030. The report said: " The main factors driving the market growth of the multiple myeloma diagnostics market are technological advancement and rising clinical studies for the management of multiple myeloma. Furthermore, rising disposable income is expected to drive the growth of the multiple myeloma diagnostic market. Government funds and initiatives for effective research and development are assisting in the discovery of new drugs for better treatment of multiple myeloma for the multiple myeloma diagnostic market. The rising prevalence of multiple myeloma is driving up demand for treatment. According to GLOBOCAN 2020 statistics… The increasing number of R&D projects to develop novel treatments for multiple myeloma is driving market growth… Such developments will also contribute to market growth." Active companies in the markets this week include: Telo Genomics Corp. (OTCQB: TDSGF) (TSXV: TELO), Bristol Myers Squibb (NYSE: BMY), Thermo Fisher Scientific Inc. (NYSE: TMO), Natera, Inc. (NASDAQ: NTRA), NeoGenomics, Inc. (NASDAQ: NEO).

Data Bridge Market Research continued: "The major factors driving market growth are strategic initiatives undertaken by market participants, increasing R&D, the growing burden of multiple myeloma, and the proven efficacy of immunomodulators… Thus, due to the above-mentioned factors, the market is expected to witness significant growth during the forecast period. U.S. dominates the multiple myeloma diagnostic market because of the favorable reimbursement policies in the region and will expect to show lucrative growth during the forecast period of 2023-2030."

Telo Genomics Corp. (OTCQB: TDSGF) (TSXV: TELO)   Engages US Diagnostics Experts to Power Product Adoption in the US   - Telo Genomics Corp. (the "Company" or "Telo") is pleased to announce that it has engaged Trusted Health Advisors (THA), a market leader specialized in guiding commercialization programs of innovative diagnostics products in the USA. THA will work with Telo's team to refine and accelerate Telo's go-to-market and partnership deployment plan, to facilitate the implementation of Telo's biomarker services for basic and clinical research and clinical diagnostic applications in Multiple Myeloma and the broader cancer field. The program will include partnerships and collaborations with basic and clinical researchers, Biopharmaceutical companies, Clinical Research Organizations (CROs), clinical laboratories and oncology providers and healthcare systems.

THA's engagement with Telo will be led by veterans in the diagnostics industry including: Jay Wohlgemuth, MD; Ray Tabibiazar, MD; Richard Bender, MD; and Mr. Paul Owen. The team will also draw on the expertise of additional THA partners ( www.trustedhealthadvisors.us ).

Dr. Wohlgemuth has many years of experience leading healthcare innovation efforts in diagnostic testing, medical devices, virtual care and digital health, and pharmaceutical and companion diagnostics development. Dr. Wohlgemuth served as CMO, CSO and SVP for Quest Diagnostics over a period of 14 years. He also served as CMO of HealthTap, as well as development team leader at Genentech / Roche for Ocrelizumab (Ocrevus) in multiple sclerosis and rheumatology, and as director of diagnostics for programs outside of oncology. Dr. Wohlgemuth was co-founder, CMO and VP R&D for CareDx, a leader in testing for transplant patients, for which he was awarded Technology Pioneer 2005 at the World Economic Forum in Davos. He also served as Chairman of the Board of the Personalized Medicine Coalition.

Dr. Tabibiazar is a seasoned executive with leadership experience in the healthcare and biopharma industries, including venture capital, pharmaceuticals and diagnostics. As a clinician-entrepreneur and managing director of " 526 Ventures ", he has focused on creating new ventures in the form of new companies or spinouts to translate innovative science into commercially viable products. Dr. Tabibiazar serves as Chair at SalioGen Therapeutics, and previously led Aravive Biologics as CEO, served as SVP, Corporate Development and Business Strategy at Twist Bioscience, and as a Venture Partner at Bay City Capital.

Dr. Bender is a board-certified oncologist who brings more than 40 years of experience in hematological malignancy with a special focus on multiple myeloma ("MM"). He received his medical degree from the UCLA School of Medicine and completed his internship and residency at UCLA-Harbor General Hospital followed by a hematology/oncology fellowship at the National Cancer Institute. His past titles include Medical Director for Hematology/Oncology for Quest Diagnostics, Medical Director for Hematology/Oncology for Kaiser Permanente, and Chief Medical Officer for both Agendia and Signal Genetics. Dr. Bender has also served on the executive board of the American Cancer Society and has been retained by the FDA as a member of the Hematology and Pathology Devices Advisory Committee. He has authored more than 80 peer-reviewed scientific articles and book chapters.

Mr. Owen most recently served as President and Interim CEO of imaware™, which provides a digital health platform experience that offers advanced home-based testing and monitoring. Mr. Owen has had a very productive and successful career in developing and bringing healthcare innovation to market. He previously served as Chief Business Officer and COO for Kailos Genetics and CEO of OneOme, an innovator in precision medicine and pharmacogenetics, co-founded by the Mayo Clinic. Prior to joining OneOme Paul led global commercialization for Invitae, a leader in diagnostics testing. Previously, Mr. Owen served as Vice Chair of Global Business Development for the Mayo Clinic and was the leader of Mayo Medical Laboratories' global commercial team, and held leadership roles at Zimmer-Biomet and Boston Scientific. CONTINUED   …   Read this full press release and more news for Telo Genomics   at: https://www.telodx.com/investors

Other recent developments in the markets of note include:

Bristol Myers Squibb (NYSE: BMY) recently announced the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended marketing authorization approval of Abecma® (idecabtagene vicleucel; ide-cel) for the treatment of adult patients with relapsed and refractory multiple myeloma who have received at least two prior therapies, including an immunomodulatory agent (IMiD), a proteasome inhibitor (PI), and an anti-CD38 monoclonal antibody. The European Commission (EC), which has the authority to approve medicines for the European Union (EU), will now review the CHMP recommendation.

"This positive CHMP opinion represents an important step toward bringing our potentially transformative first-in-class anti-BCMA CAR T cell therapy, Abecma, to more patients earlier in the multiple myeloma treatment paradigm to improve outcomes," said Anne Kerber, M.D., senior vice president and head, Late Clinical Development, Hematology, Oncology, Cell Therapy (HOCT), Bristol Myers Squibb. "We look forward to working with the European Commission with the shared goal of delivering innovative treatment options to more patients with continued unmet need."

Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, recently announced that it will release its financial results for the fourth quarter and full year 2023 before the market opens on Wednesday, January 31, 2024, and will hold a conference call on the same day at 8:30 a.m. EST.

During the call, the company will discuss its financial performance, as well as future expectations. To listen, call (833) 470-1428 within the U.S. or (404) 975-4839 outside the U.S. The access code is 718426. You may also listen to the call live on the "Investors" section of our website, www.thermofisher.com. The earnings press release and related information can also be found in that section of our website under the heading "Financials". A replay of the call will be available under "News, Events & Presentations" through Friday, February 16, 2024.

Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, recently announced that a jury in the U.S. District Court for the District of Delaware has reached a unanimous verdict in favor of Natera in its patent infringement case against CareDx, Inc.

The jury awarded Natera $83.7 million in lost profits and $12.6 million in past royalties after finding that the accused CareDx products, AlloSure and AlloSeq, infringe one of the two Natera patents asserted against CareDx, and that all asserted claims of both patents are valid on various grounds. The jury also provided an advisory verdict to the judge that all asserted claims of both patents are valid under 35 U.S.C. Sec. 101. A schedule will be set for further proceedings to determine whether CareDx's future sales of new versions of AlloSeq and AlloSure also infringe the asserted Natera patents.

Previously, Natera successfully invalidated all three of CareDx's patents that were asserted by CareDx against Natera in a separate lawsuit. The invalidity of CareDx's patents was affirmed on appeal.

NeoGenomics, Inc. (NASDAQ: NEO) , a leading oncology testing services company, recently announced that NeoGenomics Laboratories, Inc., a subsidiary of NeoGenomics Inc., will appeal the preliminary injunction issued by the United States District Court for the Middle District of North Carolina. The initial determination is that Natera, Inc. demonstrated a likelihood that products using RaDaR technology infringe one Natera, Inc. patent. The order specifically allows patients already using RaDaR to continue their use. In addition, the order explicitly allows research projects and studies that are in progress, as well as clinical trials that are in progress or have been approved, to continue.

In response to the court's ruling, Chris Smith, Chief Executive Officer of NeoGenomics said, "We continue to believe in RaDaR's innovative and distinguished technology and plan to appeal the Court's ruling and defend our technology. We remain committed to bringing our highly sensitive test to market and providing cancer patients and their clinicians with options for their care."

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DISCLAIMER: FN Media Group LLC (FNM), which owns and operates FinancialNewsMedia.com and MarketNewsUpdates.com, is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. FNM is NOT affiliated in any manner with any company mentioned herein. FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed FNM was compensated forty six hundred dollars for news coverage of the current press releases issued by Telo Genomics Corp. by a non-affiliated third party. FNM HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.

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Orchestra BioMed Reports First Quarter 2025 Financial Results and Highlights Recent Regulatory and Clinical Milestones

Orchestra BioMed Reports First Quarter 2025 Financial Results and Highlights Recent Regulatory and Clinical Milestones

  • FDA Breakthrough Device Designation Awarded to AVIM Therapy
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Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, "Orchestra BioMed" or the "Company"), a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, today announced financial results for the first quarter ended March 31, 2025, and provided a business update highlighting continued regulatory momentum, disciplined operational execution, and a strengthening clinical development pipeline.

Q1 2025 Highlights:

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Medtronic will host a video webcast at 7:00 a.m. CDT on May 21, 2025 , to discuss results for its fourth quarter and full fiscal year 2025. The webcast can be accessed at https://investorrelations.medtronic.com .

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Star Jones , award winning television personality & women's heart health advocate,   helps kick off heart health conversations this Mother's Day with the Medtronic 'Letter to My Mother' campaign

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Medtronic Affera pulsed field ablation technologies continue to demonstrate promising evidence for atrial fibrillation patients

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  • One-year clinical trial data for the next-generation, investigational, Sphere-360â„¢ single-shot PFA catheter show impressive safety, performance, and efficiency results for paroxysmal Afib
  • Dual-energy (RF/PF), focal Sphere-9â„¢ catheter demonstrates efficacy for linear ablation in persistent AFib
  • Medtronic continues legacy of leadership in innovation, showcasing arrhythmia management portfolio at Heart Rhythm Society annual meeting

Medtronic plc (NYSE: MDT), a global leader in healthcare technology, today announced positive clinical outcomes from two studies in atrial fibrillation (AFib) patients treated with the Afferaâ„¢ family of technologies, including the next-generation Sphere-360â„¢ single-shot pulsed field ablation (PFA) catheter and the groundbreaking Sphere-9â„¢ combination mapping and dual-energy focal PFA catheter. Data were presented in High Impact Science Sessions at the Heart Rhythm Society 2025 Annual Meeting in San Diego ; the Sphere-360 study was simultaneously published in the Heart Rhythm Journal .

(PRNewsfoto/Medtronic plc)

Sphere-360 Study Safety and Performance

Sphere-360 is an investigational, first-of-its-kind, single-shot PFA mapping and ablation catheter for treatment of paroxysmal atrial fibrillation (PAF). Results for Sphere-360 at one year, in a prospective, single-arm, multi-center trial performed in European centers, demonstrated freedom from arrhythmia recurrence in 88% of patients, with chronically durable pulmonary vein isolation (PVI) in 98% of targeted veins and no reported safety events in a sub-group treated with the most optimized waveform. The Sphere-360 catheter has a large, conformable lattice design that can be modified into various shapes, is seamlessly integrated with the Affera Mapping and Ablation System and utilizes an 8.5 Fr sheath – the smallest in any single-shot PFA technology.

"The Affera technology is a sophisticated ecosystem, including an advanced, intuitive mapping system and catheters that are seamlessly integrated to offer treatment options for different cardiac arrhythmias. It is encouraging to see the promising results for Sphere-360, which can easily create circumferential lesions without the need for catheter rotation," said Vivek Reddy , M.D., Director of Cardiac Arrhythmia Services for the Mount Sinai Health System in New York City . "The study results showed Sphere-360 has a promising safety and performance profile with zero serious adverse events observed. Upon approval, Sphere-360 will be a valuable addition to Medtronic's Affera system, which has been a game changer for Afib treatment and physician workflow."

Medtronic intends to begin its U.S. pivotal trial for the Sphere-360 catheter later this calendar year. Worldwide, Sphere-360 is currently investigational and not approved for sale or distribution.

Sphere-9 for Linear Ablation

Additionally, in a sub-analysis from the Sphere Per-AF IDE study , results demonstrated that the Sphere-9 catheter can be used safely and effectively to create linear lesions in persistent AF patients. Linear ablation is often used in conjunction with PVI to improve the chances of restoring a normal heart rhythm without recurrence in persistent AF patients. The Sphere Per-AF IDE study evaluated the safety, efficacy and efficiency of Affera and Sphere-9 in persistent AF and led to the FDA approval of Affera in October 2024 .

"True to our Medtronic mission for patients and legacy of innovation, we are delivering our best-in-class technologies to physicians and improving care for AFib patients, and we are not slowing down," said Rebecca Seidel , president of the Cardiac Ablation Solutions business at Medtronic, which is part of the Cardiovascular portfolio. "These results signify another step forward and energize us as we continue to earn and build our leadership position in electrophysiology every day."

Medtronic is the only company with two PFA offerings for physicians and patients. The PulseSelectâ„¢ Pulsed Field Ablation System offers physicians a safe, single-shot solution for pulmonary vein isolation (PVI) and is now available in more than 30 countries. The Affera system together with the Sphere-9 catheter enables physician treatment flexibility with its wide area focal design and 9mm lattice tip that can used with an 8.5Fr sheath. Affera is available in Europe , Australia and New Zealand , with global expansion ongoing.

AFib is one of the most common and undertreated heart rhythm disorders, affecting more than 60 million people worldwide. 1 Afib is a progressive disease, often beginning as paroxysmal AFib (presents intermittently) and progressing to persistent (lasts for more than 7+ days without stopping). As the disease progresses, the risk of serious complications including heart failure, stroke and risk of death increases 2-5 .

For more information on the Affera PFA system and the Sphere-9 catheter, visit Medtronic.com.

About Medtronic

Bold thinking. Bolder actions. We are Medtronic. Medtronic plc, headquartered in Galway , Ireland , is the leading global healthcare technology company that boldly attacks the most challenging health problems facing humanity by searching out and finding solutions. Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people across more than 150 countries. Our technologies and therapies treat 70 health conditions and include cardiac devices, surgical robotics, insulin pumps, surgical tools, patient monitoring systems, and more. Powered by our diverse knowledge, insatiable curiosity, and desire to help all those who need it, we deliver innovative technologies that transform the lives of two people every second, every hour, every day. Expect more from us as we empower insight-driven care, experiences that put people first, and better outcomes for our world. In everything we do, we are engineering the extraordinary. For more information on Medtronic (NYSE: MDT), visit www.Medtronic.com and follow Medtronic on LinkedIn .

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.

References

  1. Roth GA, Mensah GA, Johnson CO et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol 2020;76:2982-3021.
  2. Miyasaka Y, Barnes ME, Bailey KR, et al. Mortality trends in patients diagnosed with first atrial fibrillation: a 21-year community-based study. J Am Coll Cardiol 2007;49:986-92.
  3. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS). Eur Heart J 2020.
  4. Wolf PA , Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983-8.
  5. Lubitz SA, Moser C, Sullivan L, et al. Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community. J Am Heart Assoc 2013;2:e000126

Dr. Reddy is a paid consultant for Medtronic.

Contacts:
Leslie Williamson
Public Relations
+1-612-227-5099

Ryan Weispfenning
Investor Relations
+1-763-505-4626

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SOURCE Medtronic plc

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