Atara Biotherapeutics Highlights Next-Generation and Off-the-Shelf, Allogeneic CAR T Technologies and Pipeline

Atara Biotherapeutics (Nasdaq:ATRA), a leading off-the-shelf, allogeneic T-cell immunotherapy company developing novel treatments for patients with cancer, autoimmune and viral diseases, today presented details of the Company’s next-generation chimeric antigen receptor T cell (CAR T) technologies and pipeline in conjunction with hosting a CAR T Breakfast Teach-In event in New York, NY.

As quoted in the press release:

Dr. Sadelain described CAR T technologies including novel co-stimulatory domains modified to generate more physiologic signaling, reduce exhaustion, improve persistence and unlock the solid tumor microenvironment.  Atara and MSK are collaborating to develop next-generation CAR T immunotherapies using several of these innovative CAR T technologies.

Dr. Davila’s presentation focused on developing promising CAR T immunotherapies for patients with AML and B cell malignancies in collaboration with Atara using modified co-stimulatory subdomains designed to improve persistence and reduce T cell exhaustion.

Dietmar Berger, M.D., Ph.D., Global Head of Research & Development of Atara Biotherapeutics introduced the Company’s strategy to leverage these innovative licensed technologies with Atara’s EBV-specific T cell expertise to advance next-generation, off-the-shelf CAR T programs.

Click here to read the full press release.