Life Science News

Sirona Biochem Corp . (TSX-V: SBM) (FSE: ZSB) (OTC: SRBCF) (" Sirona ") is pleased to provide the following update to shareholders.

Dear shareholders,

We provide this update with conviction that value-driving developments ahead will open a new chapter in Sirona's history. Admittedly, we expected it in 2021, but some events with our partners could not be foreseen.

We thank everyone for their continued support and remain committed to creating value for shareholders with expanding partnerships globally.


We are in the negotiation phase with a global top 10 pharmaceutical company for the rights to TFC-1067. We are completing final legal due diligence and they are advancing on the project as expected. They remain transparent on their steps and timelines.

We are very pleased to have the engagement of Linda Pullan and Pullan Consulting team to assist with this negotiation Linda has successfully closed many pharma/biotech deals and is a renowned professional in the field. She will provide strategic direction negotiating and closing this deal.

We continue to discuss TFC-1067 with other potential global and regional partners and will highlight the compound at BIO JPM January 10th – 14th. Partnering the compound remains a top priority for the company.

Our partnership with Rodan + Fields (R+F) remains strong. We expect to receive their forecasted 2022 requirements for TFC-1067within the next month and currently maintain a sufficient inventory of product.


Individual countries have regulatory requirements which can differ from the rest of the world. The full library of compounds (which includes TFC-1067 as well as TFC-1394) will provide a path to navigate various regions and offer partnerships beyond just the initial compound.

In the event that the licensee of TFC-1067 wishes to also license the whole library, the value of the transaction will reflect this.


As recently announced, Wanbang Biopharmaceuticals has notified us of their decision to discontinue the development of TFC-039 for the treatment of type 2 diabetes in China. While this is disappointing, we still see opportunity ahead for TFC-039 and value added by the work completed to date.

We have refocused our efforts on TFC-039 and have adjusted our strategy to develop the drug for a patentable new indication that addresses unmet needs in valuable markets. Unlike the current indication of diabetes, the new target will put us ahead of any competition. We also have scientific reason to believe there is strong advantages for TFC-039 compared to other compounds of the same class.

We have begun studies on this new indication to determine the preclinical activity and are securing the necessary intellectual property. Details of the new indication cannot be disclosed, but the opportunity as a valuable therapeutic exists and is an area of great need.

Animal Health

This month, we will continue our meetings with two global companies in animal health. Our original party was impacted significantly by a merger, which concluded with the shuffling of senior management, R&D and the external innovation experts. We have re-engaged with a new senior person in the company and will revisit the project in January. Having excellent data already obtained, we remain hopeful to get this project partnered.


The lead compound for anti-aging is currently entering into the development of the analytical method by our manufacturing partner. This is a necessary step in order to qualify the profile of the batch produced for the clinical trial. Once this is established, we will begin with a small scale-up in house to develop the formulation that can be used in a clinical trial as well as for stability studies. A small scale up will also be initiated at a contract manufacturer. Simultaneously, we are speaking with potential partners for R&D collaborations.

At present, we anticipate the clinical trial to take place in the second half of 2022.


We are excited to report that we now have 20 compounds that entered testing for anti-COVID activity. These can take up to 6 weeks to complete and we expect results by the end of February 2022.

In terms of partnering, we seek partners at any stage of development. However, the company will move forward with testing regardless of having a partner. If development advances beyond the preclinical stage, we will likely require a partner to share the cost of clinical trials. With enough preclinical activity to move to clinical, we do not anticipate difficulty in finding that partner.

We are currently in discussions with another biotech company that possesses a high level of expertise in developing antivirals. We are also exploring non-dilutive government funding, which has become more readily available in the current pandemic.


The anti-cellulite project is early stage, but exciting in that there's no competition that offer real treatment potential currently in the market. This makes it a desirable target for skincare companies. At this time, we are in discussions with a top pharmaceutical company and the next step will be a presentation to their R&D team on the development plan. This will occur within the next weeks.


We are very much looking forward to participating in "BIO Partnering at JPM" by Biotechnology Innovation Organization from January 10-14, 2022. Meetings have been arranged and preparations are underway. JPM is the perfect forum to present each of the above projects.

Grant of Incentive Stock Options

Sirona announces that it has granted an aggregate of 4,000,000 incentive stock options to management, independent directors and consultants of the Company. The options may be subject to performance-based vesting provisions as determined by the board of directors. The options, to purchase common shares in the capital of the Company, at a price of $0.17 per common share, will be for periods ranging from 5 to 10 years. The options have been granted under the terms of the Company's stock option plan.

Dr. Howard Verrico, CEO

About Sirona Biochem Corp.

Sirona Biochem is a cosmetic ingredient and drug discovery company with a proprietary platform technology. Sirona specializes in stabilizing carbohydrate molecules with the goal of improving efficacy and safety. New compounds are patented for maximum revenue potential.

Sirona's compounds are licensed to leading companies around the world in return for licensing fees, milestone fees and ongoing royalty payments. Sirona's laboratory, TFChem, is in France and is the recipient of multiple French national scientific awards and European Union and French government grants. For more information, please visit .

For more information regarding this press release, please contact:

Investor Enquiries:
Jonathan Williams
Managing Director
Momentum PR
Phone: 1.450.332.6939

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise. Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem's forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem's business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

Primary Logo

News Provided by GlobeNewswire via QuoteMedia

Sirona Biochem Inc.

Sirona Biochem Inc.


Sirona Biochem Inc. (TSXV:SBM) is a biotechnology company with an innovative platform for developing safer, more effective cosmetic and pharmaceutical active ingredients. The technology is based on proprietary fluorination chemistry developed by the company’s wholly-owned French subsidiary, research and development (R&D) laboratory TFChem. Sirona Biochem’s business model centers on leveraging its technology platform and chemistry expertise to build strategic R&D partnerships with leading global companies through contract services, licensing and royalty agreements as well as joint ventures.

TFChem has developed a fluorination chemistry that can improve the safety and efficacy of carbohydrate-based molecules. Carbohydrate-based molecules are valuable in that they have broad application potential for the development of pharmaceuticals and cosmeceuticals. Examples of commercially available carbohydrate-based drugs include viral neuraminidase inhibitor Tamiflu, and Johnson & Johnson’s (NYSE:JNJ) SGLT2 inhibitor Invokana™. However, carbohydrate-based molecules are extremely challenging to develop due to their inherent instability. Sirona Biochem’s proprietary chemistry technique overcomes that challenge by stabilizing carbohydrates, allowing the company to explore commercial opportunities for these valuable molecules.

Sirona Biochem’s product pipeline includes an SGLT2 inhibitor for the treatment of type 2 diabetes as well as cosmeceuticals such as compound libraries for safe and effective skin lighteners and anti-aging compounds. The company has completed two successful licensing agreements. The first, for its SGLT2 inhibitor to Wanbang/Fosun Pharmaceutical in China, which is now in advanced Phase I clinical trials. The second was a non-exclusive license to Rodan + Fields, the leading skin care brand in the United States, for Sirona’s skin lightening compound TFC-1067. The compound has proven safe and effective in clinical trials.

Sirona Biochem is led by a highly experienced team of finance and biotechnology professionals. The company’s Chief Scientific Officer Dr. Géraldine Deliencourt-Godefroy is an award-winning synthetic chemist and the founder of the French biotechnology company TFChem. Her scientific research in carbohydrate chemistry has led to the discovery of new drug families and the development of drug candidates for diabetes and obesity, cosmetic ingredients and biological adjuvants. She is the recipient of the acclaimed Francinov Research and Innovation Medal, the French Ministry of Research Award and the French Senate Award.

Keep reading... Show less
Sirona Biochem Antiviral Compounds to be Tested Against SARS-CoV-2 by Top US Testing Facility

Sirona Biochem Antiviral Compounds to be Tested Against SARS-CoV-2 by Top US Testing Facility

Sirona Biochem Corp . (TSXV: SBM) (FSE: ZSB) (OTC: SRBCF) (" Sirona ") announces the advancement of 20 antiviral compounds to In Vitro testing. The compounds will be shipped to the Utah State University's Institute of Antiviral Research for evaluation against the SARS-CoV-2 virus (COVID-19).

Keep reading... Show less
Sirona Biochem Provides Update on SGLT2 Inhibitor for Type 2 Diabetes in China

Sirona Biochem Provides Update on SGLT2 Inhibitor for Type 2 Diabetes in China

Sirona Biochem Corp . (TSXV: SBM) (FSE: ZSB) (OTC: SRBCF) (" Sirona ") announces that it has received notice that the development of Sirona's SGLT2 inhibitor, TFC-039, will be discontinued by Wanbang Biopharmaceuticals (" Wanbang ") as a treatment for type 2 diabetes in China .

Keep reading... Show less
sbm tsx

Sirona Biochem Announces 2021 Annual Meeting Results: Shareholders Approve All Resolutions With Majority Vote

Sirona Biochem Corp . (TSXV: SBM) (FSE: ZSB) (OTC: SRBCF)  (" Sirona ") is pleased to announce the voting results from its Annual General Meeting of Shareholders (the "Meeting"), held in Vancouver, British Columbia on November 10, 2021 . The total number of shares represented by shareholders present in person and by proxy at the meeting was 33,335,079, representing 14.45% of Sirona's issued and outstanding Common Shares.

Keep reading... Show less
sirona biochem

/R E P E A T -- Sirona Biochem: Investing News Network Interview with CEO, Dr. Howard Verrico/

Featuring an update on anticipated deal for TFC-1067

Sirona Biochem Corp . (TSXV: SBM) (FSE: ZSB) (US-OTC: SRBCF) (" Sirona ") is pleased to inform its shareholders that a video interview with CEO, Dr. Howard Verrico has been published by Investing News Network in Vancouver BC Canada .

Keep reading... Show less

Sirona Biochem: Investing News Network Interview with CEO, Dr. Howard Verrico

Featuring an update on anticipated deal for TFC-1067

Sirona Biochem Corp . (TSXV: SBM) (FSE: ZSB) (US-OTC: SRBCF) (" Sirona ") is pleased to inform its shareholders that a video interview with CEO, Dr. Howard Verrico has been published by Investing News Network in Vancouver BC Canada .

Keep reading... Show less

The Gross Law Firm Announces Class Actions on Behalf of Shareholders of ABBV, NTRA and CDNA

The securities litigation law firm of The Gross Law Firm issues the following notice on behalf of shareholders in the following publicly traded companies. Shareholders who purchased shares in the following companies during the dates listed are encouraged to contact the firm regarding possible Lead Plaintiff appointment. Appointment as Lead Plaintiff is not required to partake in any recovery


Keep reading... Show less

ABBV ALERT: Kessler Topaz Meltzer & Check, LLP Reminds Investors of Securities Fraud Class Action Lawsuit Filed Against AbbVie, Inc.

The law firm of Kessler Topaz Meltzer & Check, LLP( informs investors that the firm has filed a securities class action lawsuit against ABBVie, Inc. (ABBVie) (NYSE:ABBV) on behalf of all persons and entities who purchased or otherwise acquired ABBVie securities between April 30, 2021, and August 31, 2021, inclusive (the "Class Period


Keep reading... Show less

The Klein Law Firm Reminds Investors of Class Actions on Behalf of Shareholders of ABBV, NTRA and CDNA

The Klein Law Firm announces that class action complaints have been filed on behalf of shareholders of the following companies. There is no cost to participate in the suit. If you suffered a loss, you have until the lead plaintiff deadline to request that the court appoint you as lead plaintiff

Class Period: April 30, 2021 - August 31, 2021
Lead Plaintiff Deadline: June 6, 2022

Keep reading... Show less

CLASS ACTION UPDATE for VLTA, LCID and AUPH: Levi & Korsinsky, LLP Reminds Investors of Class Actions on Behalf of Shareholders

Levi & Korsinsky, LLP announces that class action lawsuits have commenced on behalf of shareholders of the following publicly-traded companies. Shareholders interested in serving as lead plaintiff have until the deadlines listed to petition the court. Further details about the cases can be found at the links provided. There is no cost or obligation to you

VLTA Shareholders Click Here:
LCID Shareholders Click Here:
AUPH Shareholders Click Here:

Keep reading... Show less

Aptose to Provide Program Updates at KOL Webinar on Thursday, June 2nd

Aptose Biosciences Inc. (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral kinase inhibitors to treat hematologic malignancies, today announced that it will host a key opinion leader (KOL) webinar on HM43239 and luxeptinib and their roles in the treatment of acute myeloid leukemia (AML) on Thursday, June 2, 2022 at 4:30 pm Eastern Time.

The call will feature KOLs Brian Druker, M.D., of the Oregon Health & Science University, Naval G. Daver, M.D., of The University of Texas MD Anderson Cancer Center, and Brian Andrew Jonas, M.D., Ph.D., of the University of California, Davis, who will discuss the current treatment landscape and unmet medical need in treating patients with acute myeloid leukemia AML, as well as their experiences with Aptose's investigational therapies.

Keep reading... Show less

AbbVie to Present at the Bernstein 38th Annual Strategic Decisions Conference

ABBVie (NYSE: ABBV) will participate in the Bernstein 38 th Annual Strategic Decisions Conference on Wednesday, June 1, 2022 . Richard A. Gonzalez chairman and chief executive officer, will present at 10:00 a.m. Central Time .

A live audio webcast of the presentation will be accessible through AbbVie's Investor Relations website at An archived edition of the session will be available later that day.

Keep reading... Show less

Latest Press Releases

Related News