Adicet Bio Appoints Michael Grissinger to the Board of Directors

--Mr. Grissinger brings more than four decades of leadership experience in pharmaceutical business development and strategic transactions--

Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer, today announced the appointment of Michael Grissinger to its Board of Directors. Mr. Grissinger brings more than four decades of experience in business development, strategy, and M&A leadership roles at global pharmaceutical companies.

"We are honored to welcome Michael to our Board of Directors," said Chen Schor, President and Chief Executive Officer of Adicet Bio. "His extensive operational and business development experience across the global pharmaceutical industry, especially his deep expertise in immunology, brings a wealth of knowledge and invaluable strategic insight to Adicet. Michael's notable accomplishments in driving business and commercial success will be instrumental in shaping the next stage of our growth as we continue to advance our gamma delta T cell platform for the treatment of autoimmune and solid tumor indications."

Mr. Grissinger spent more than two decades at Johnson & Johnson. During his Johnson & Johnson tenure, Mr. Grissinger served in a variety of senior level management roles including Vice President and Head of Worldwide Pharmaceutical Licensing and Vice President and Head of Worldwide Pharmaceutical Corporate Development and M&A. At Johnson & Johnson, Mr. Grissinger led the Immunology Therapeutic Area Business Development and Licensing Group and was also a member of the Immunology R&D/ Commercial leadership team for Johnson & Johnson's Worldwide Immunology Franchise. Prior to Johnson & Johnson, Mr. Grissinger spent 12 years at Ciba-Geigy in finance, marketing and business development roles. Mr. Grissinger also serves on the board of directors at Aprea Therapeutics (Nasdaq: APRE) and three privately-held biotechnology companies, Envisagenics, Inc., AnaCardio AB, and NephroDI Therapeutics, Inc. Mr. Grissinger holds a B.S. in Chemistry from Juniata College and an M.B.A. from Temple University-Fox School of Business.

"I am pleased to join the Board of Adicet, a company rooted in harnessing the power of the immune system by developing off-the-shelf gamma delta CAR T cell therapies to make a meaningful difference in patients' lives," said Mr. Grissinger. "I look forward to working alongside the Board and management team and contributing to the advancement of current pipeline programs focused on autoimmune and oncology indications."

Forward-Looking Statements

This press release contains "forward-looking statements" of Adicet within the meaning of the Private Securities Litigation Reform Act of 1995 relating to the business and operations of Adicet. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. These forward-looking statements include, but are not limited to, express or implied statements regarding: expectations related to Adicet's business development, strategic opportunities and growth; Adicet's plans and expectations for advancing its autoimmune programs across multiple autoimmune and solid tumor indications; and the anticipated contribution of the members of Adicet's Board of Directors to the Company's business.

Any forward-looking statements in this press release are based on management's current expectations and beliefs of future events, and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements, including without limitation, the effect of global economic conditions and public health emergencies on Adicet's business and financial results, including with respect to disruptions to our preclinical and clinical studies, business operations, employee hiring and retention, and ability to raise additional capital; Adicet's ability to execute on its strategy including obtaining the requisite regulatory approvals on the expected timeline, if at all; that positive results, including interim results, from a preclinical or clinical study may not necessarily be predictive of the results of future or ongoing studies; clinical studies may fail to demonstrate adequate safety and efficacy of Adicet's product candidates, which would prevent, delay, or limit the scope of regulatory approval and commercialization; and regulatory approval processes of the U.S. Food and Drug Administration and comparable foreign regulatory authorities are lengthy, time-consuming, and inherently unpredictable; and Adicet's ability to meet production and product release expectations. For a discussion of these and other risks and uncertainties, and other important factors, any of which could cause Adicet's actual results to differ from those contained in the forward-looking statements, see the section entitled "Risk Factors" in Adicet's most recent quarterly report on Form 10-Q and subsequent filings with the U.S. Securities and Exchange Commission (SEC), as well as discussions of potential risks, uncertainties, and other important factors in Adicet's other filings with the SEC. All information in this press release is as of the date of the release, and Adicet undertakes no duty to update this information unless required by law.

Adicet Bio, Inc.  
Investor and Media Contacts

Investors:  
Anne Bowdidge
abowdidge@adicetbio.com

Janhavi Mohite
Precision AQ
212-362-1200
janhavi.mohite@precisionaq.com

Media:  
Kerry Beth Daly
kbdaly@adicetbio.com

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Adicet Bio Inc.

Adicet Bio Inc is a clinical-stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer and other diseases. The company is advancing a pipeline of off-the-shelf gamma delta T cells, engineered with chimeric antigen receptors and T cell receptor-like antibodies to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients.

Bayan Secures Transformative Patents in Solar Cell Recycling Technology

Bayan Secures Transformative Patents in Solar Cell Recycling Technology

Bayan Mining and Minerals Ltd (ASX: BMM; "BMM" or "the Company") is pleased to announce that it has reached an agreement to exclusively licence IP from Macquarie University for its Solar Cell Recycling Technology. A summary of the material terms of the agreement are set out in Schedule 1. This agreement is a key milestone in Bayan’s strategic growth, enabling the Company to take advantage of a major economic opportunity in the critical mineral recycling/recovery market.

Highlights

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Nextleaf Solutions Awarded U.S. Patent for Synthesizing CBG-O-Acetate

Nextleaf Solutions Awarded U.S. Patent for Synthesizing CBG-O-Acetate

CBG-O-Acetate added to the Company's Specialty Molecules Division

Nextleaf Solutions Ltd. (CSE: OILS) (OTCQB: OILFF) ("Nextleaf", "OILS", or the "Company"), a federally regulated cannabis oil producer that owns one of the largest portfolios of U.S. patents for the extraction and distillation of cannabinoids, is pleased to announce that the United States Patent and Trademark Office has granted the Company a patent pertaining to a novel process for acetylating Cannabigerol ("CBG"), and subsequent refinement of CBG-O-Acetate.

Acetylation is an organic esterification reaction, which often utilizes acetic acid. Examples of acetylated pharmaceuticals include Aspirin (acetylsalicylic acid) and diacetylmorphine. The Company was previously granted U.S. and Canadian patents for the acetylation of both CBD and THC, and subsequent refinement of CBD-O-Acetate and THC-O-Acetate. THC-O-Acetate acts as a metabolic prodrug for THC itself, and chemically works the same way that diacetylmorphine does as a metabolic prodrug for morphine.

The Company's latest U.S. patent describes its proprietary production process of modifying CBG found in cannabis distillate into a prodrug, referred to as CBG-O-Acetate. As CBG-O-Acetate is metabolized in the body, the acetate group is removed, allowing the CBG to interact with the cannabinoid receptors.

"CBG is often referred to as the mother cannabinoid as so many other cannabinoids can be derived from its acidic form," said patent author and Nextleaf Solutions Chief Technology Officer Ryan Ko. "This issuance provides further validation for our specialty molecules development roadmap."

The Company believes the CBG-derived prodrug produced under its patented process may hold significant potential as a therapeutic product based on research that CBG may be effective in the treatment of inflammation, pain, and nausea. Peer-reviewed research also suggests that CBG in higher doses may be beneficial in treating conditions such as Crohn's disease1 and cancer2.

Nextleaf owns 16 issued U.S. patents and over 80 issued patents globally for the extraction, purification, and delivery of cannabinoids - representing the third largest patent portfolio amongst all cannabis companies after Canopy Growth and GW Pharma.

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"We are thrilled to enhance our U.S. patent portfolio with this novel production process, that along with our Health Canada licenses, allows Nextleaf to develop and produce truly differentiated cannabinoid-based products through our Specialty Molecules Division," said Nextleaf Solutions co-founder and Chief Executive Officer Paul Pedersen. "To the best of our knowledge, Nextleaf is the first company in the world - publicly traded or private - to be issued patents for the production of CBG-O-Acetate, a specialty molecule not legally available anywhere in the world."

The purpose of the Specialty Molecules Division is to leverage Nextleaf's existing intellectual property ("IP") and delivery technology to develop IP-protected therapeutic products from novel molecules that may provide a therapeutic alternative to opioid-based medications.

About Nextleaf®

Nextleaf is a federally regulated producer of cannabis oil that owns one of the largest portfolios of U.S. patents for the extraction and distillation of cannabinoids. Nextleaf supplies cannabis oils to its wholesale customers and distributes consumer products under its award-winning prohibition-era brand, Glacial Gold™. Nextleaf's proprietary closed-loop automated extraction plant in Metro Vancouver has a design capacity to process 600 kilos of dried cannabis into oil per day. Nextleaf is developing delivery technology through its Health Canada Research Licence with sensory evaluation of cannabis via human testing. The Company owns 16 U.S. patents and has been issued over 80 patents globally.

Nextleaf Solutions trades as OILS on the Canadian Securities Exchange, OILFF on the OTCQB Market in the United States, and L0MA on the Frankfurt Stock Exchange.

Follow Glacial Gold™ across social platforms: Instagram, Twitter, and Facebook.
www.glacial.gold

Follow the Company across social platforms: Twitter, LinkedIn, Facebook, and Instagram.
www.nextleafsolutions.com

For more information please contact:
Jason McBride, Corporate Development
604-283-2301 (ext. 219)
jason@nextleafsolutions.com

On behalf of the Board of Directors of the Company,
Paul Pedersen, CEO

Certain statements contained in this press release constitute "forward-looking statements". All statements other than statements of historical fact contained in this press release, including, without limitation, those regarding the Company's ability to capitalize on its IP portfolio,the Company's strategy, plans, objectives, goals and targets, and any statements preceded by, followed by or that include the words "believe", "expect", "aim", "intend", "plan", "continue", "will", "may", "would", "anticipate", "estimate", "forecast", "predict", "project", "seek", "should" or similar expressions or the negative thereof, are forward-looking statements. These statements are not historical facts but instead represent only the Company's expectations, estimates and projections regarding future events. These statements are not guarantees of future performance and involve assumptions, risks and uncertainties that are difficult to predict. Therefore, actual results may differ materially from what is expressed, implied or forecasted in such forward-looking statements. Additional factors that could cause actual results, performance or achievements to differ materially include, but are not limited to the risk factors discussed in the Company's MD&A for the most recent fiscal period. Management provides forward-looking statements because it believes they provide useful information to investors when considering their investment objectives and cautions investors not to place undue reliance on forward-looking information. Consequently, all of the forward-looking statements made in this press release are qualified by these cautionary statements and other cautionary statements or factors contained herein, and there can be no assurance that the actual results or developments will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, the Company. These forward-looking statements are made as of the date of this press release and the Company assumes no obligation to update or revise them to reflect subsequent information, events or circumstances or otherwise, except as required by law. The CSE has not reviewed or approved the contents of this press release.

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nextleaf

Nextleaf Solutions Provides Commentary on Restated Q3 Financial Results

Nextleaf Solutions Ltd. (CSE: OILS) (OTCQB: OILFF) ("Nextleaf", "OILS", or the "Company"), a federally regulated cannabis oil producer that owns one of the largest portfolios of U.S. patents for the extraction, distillation, and delivery of cannabinoids, released restated Q3 financials today. Subsequent to the filing of the financial statements and management's discussion and analysis for the three and nine month period ended June 30, 2021, the Company identified calculation and input errors which have been corrected in the amended and restated financial statements and management's discussion and analysis. The Company notes that the restatement has minimal bearing on the historical and ongoing operating performance of the Company.

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Nextleaf Launches Specialty Molecules Division

Nextleaf Launches Specialty Molecules Division

THC-O-Acetate to be Produced Through Company's Specialty Molecule Division

Nextleaf Solutions Ltd. (CSE: OILS) (OTCQB: OILFF) ("Nextleaf", "OILS", or the "Company"), an extraction company that owns one of the largest portfolios of U.S. patents for the extraction and distillation of cannabinoids, is pleased to announce the launch of a Specialty Molecules Division to focus on the development and commercialization of novel psychoactive compounds. The division is supported by the Company's existing intellectual property ("IP") portfolio, including the manufacturing of CBD-O-acetate and the recently announced U.S. patent for the synthesis of THC-O-acetate.

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nextleaf solutions

Nextleaf Solutions Provides Q2 Update

Nextleaf Solutions Ltd. (CSE: OILS) (OTCQB: OILFF) ("Nextleaf", "OILS", or the "Company"), the world's most innovative cannabis extractor, is pleased to provide shareholders with the following commercial update and comments on its second-quarter results:

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Nextleaf Provides Commercial Update

Nextleaf is pleased to announce that subsequent to the quarter-end it completed the second wholesale order from its recently announced customer, a NASDAQ-listed global cannabis company (the "Partner"). The Company's wholly-owned subsidiary Nextleaf Labs Ltd. ("Nextleaf Labs" or "Labs") supplies the Partner with high-purity CBD distillate to power their branded CBD oil products that are distributed by provincially-authorized retailers across Canada.

Additionally, the Company is pleased to announce Nextleaf Labs has onboarded an Ontario licensed producer (the "New Partner") and received an initial purchase order for approximately 40 kilos of high-purity THC distillate. The New Partner plans to use Nextleaf's THC distillate to power their market-leading vape brand.

"We are thrilled that our two newest partners are leveraging Nextleaf's competitive advantage to power their established brands," said Nextleaf Solutions CEO Paul Pedersen. "We continue to expand our B2B wholesale business, supplying some of the world's largest cannabis producers with THC and CBD oils produced by Nextleaf's patented cannabis oil refinery. With the recent issuance of our sales amendment by Health Canada, Nextleaf looks forward to increasing revenues through the sale of branded consumer cannabis products by provincially-authorized retailers," said Pedersen.

Q2 Highlights and Recent Developments

In the second quarter, Nextleaf Solutions continued to execute on its corporate strategy and advance its commercial operations, as illustrated by the following milestones:

  • The United States Patent and Trademark Office granted Nextleaf three distinct patents related to the extraction, purification, and delivery of cannabinoids, adding to the Company's dynamic and expanding portfolio of issued U.S. patents.
  • The Canadian Intellectual Property Office granted Nextleaf a patent for the acetylation of cannabinoids. More specifically, the patent covers a process for acetylating CBD, and subsequent refinement of CBD-O-Acetate using a proprietary extraction and distillation technique.
  • The Israeli Patent Office granted the Company a patent for its foundational process for producing low-cost cannabis distillate, Nextleaf's fifth issued extraction patent in Israel.
  • The Mexican Institute of Industrial Property granted Nextleaf a patent vital to the low-cost production of cannabis distillate.
  • Nextleaf Labs received an amendment to its existing Cannabis Research Licence from Health Canada to conduct controlled human administration trials for sensory evaluation of cannabis. This license permits Nextleaf Labs to conduct R&D involving the administration of cannabis to human subjects for the assessment of taste, sight, or smell, subject to conditions laid out by Health Canada.
  • Nextleaf Labs received an amendment to its existing Standard Cannabis Processing Licence from Health Canada that authorizes the sale of cannabis extracts, edibles, and topical products, directly to provincially-authorized distributors and retailers across Canada.
  • Nextleaf closed a private placement with an institutional investor (the "Investor") for aggregate gross proceeds of $3,000,000 (the "Offering"). The Offering was completed pursuant to the terms of securities purchase agreement dated March 31, 2021, between the Company and the Investor which provided for the issuance of a senior secured convertible note of the Company in the principal amount of $3,300,000 and a warrant to purchase up to 6,875,000 common shares in the capital of the Company.

Nextleaf Comments on Financial Results from Q2 Financials

The second quarter saw an increased operational focus on both finalization of Nextleaf's sales amendment, which was received shortly after the quarter-end, and optimization and scaling of vape cartridge manufacturing line, capable of producing up to 8,000 vape cartridges per day. With capital expenditures tapering off significantly and overheads tightening, Nextleaf's expect to be well positioned to grow its B2B segment, consistently as the overall market moves toward equilibrium.

"Beyond turning initial B2B orders into longer-term supply agreements, increased revenue optionality is key to be building a sustainable business model. We've built a facility, team, and IP base that has synergies through all three of our revenue pillars of IP licensing, B2B bulk sales, and B2C branded product sales. We believe a diverse revenue model, with commonalties will allow us to build a very sustainable business in the medium term, while smoothing revenues as the B2B market normalizes," said Nextleaf CFO Charles Ackerman. "Due to a focus on automation, as Nextleaf's facility utilization increases - further operational synergies should be realized, providing the ability to drive costs down and provide more value to our partners," said Ackerman.

About Nextleaf®

Nextleaf is an innovative cannabis processor that owns one of the largest portfolios of U.S. patents for the extraction, distillation, and delivery of cannabinoids. Nextleaf supplies cannabis oils to its wholesale customers and distributes consumer products under its award-winning prohibition-era brand, Glacial Gold™. Nextleaf's proprietary closed-loop automated extraction plant in Metro Vancouver has a design capacity to process 600 kilos of dried cannabis into oil per day. Nextleaf is developing delivery technology through its Health Canada Research Licence with sensory evaluation of cannabis via human testing.

The Company owns 14 U.S. patents and has been issued 80 patents globally.

Nextleaf Solutions trades as OILS on the Canadian Securities Exchange, OILFF on the OTCQB Market in the United States, and L0MA on the Frankfurt Stock Exchange.

Follow OILS across social media platforms: Twitter, LinkedIn, Facebook, and Instagram.

www.nextleafsolutions.com

For more information please contact:
Jason McBride
604-283-2301 (ext. 219)
investors@nextleafsolutions.com

On behalf of the Board of Directors of the Company,
Paul Pedersen, CEO

Certain statements contained in this press release constitute "forward-looking statements". All statements other than statements of historical fact contained in this press release, including, without limitation, those regarding the Company's ability to capitalize on its IP portfolio,the Company's strategy, plans, objectives, goals and targets, and any statements preceded by, followed by or that include the words "believe", "expect", "aim", "intend", "plan", "continue", "will", "may", "would", "anticipate", "estimate", "forecast", "predict", "project", "seek", "should" or similar expressions or the negative thereof, are forward-looking statements. These statements are not historical facts but instead represent only the Company's expectations, estimates and projections regarding future events. These statements are not guarantees of future performance and involve assumptions, risks and uncertainties that are difficult to predict. Therefore, actual results may differ materially from what is expressed, implied or forecasted in such forward-looking statements. Additional factors that could cause actual results, performance or achievements to differ materially include, but are not limited to the risk factors discussed in the Company's MD&A for the most recent fiscal period. Management provides forward-looking statements because it believes they provide useful information to investors when considering their investment objectives and cautions investors not to place undue reliance on forward-looking information. Consequently, all of the forward-looking statements made in this press release are qualified by these cautionary statements and other cautionary statements or factors contained herein, and there can be no assurance that the actual results or developments will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, the Company. These forward-looking statements are made as of the date of this press release and the Company assumes no obligation to update or revise them to reflect subsequent information, events or circumstances or otherwise, except as required by law. The CSE has not reviewed or approved the contents of this press release.

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