AbbVie Reports First-Quarter 2025 Financial Results

Reports First-Quarter Diluted EPS of $0.72 on a GAAP Basis, a Decrease of 6.5 Percent; Adjusted Diluted EPS of $2.46 , an Increase of 6.5 Percent; These Results Include an Unfavorable Impact of $0.13 Per Share Related to Acquired IPR&D and Milestones Expense
Delivers First-Quarter Net Revenues of $13.343 Billion , an Increase of 8.4 Percent on a Reported Basis or 9.8 Percent on an Operational Basis
First -Quarter Global Net Revenues from the Immunology Portfolio Were $6.264 Billion , an Increase of 16.6 Percent on a Reported Basis, or 18.1 Percent on an Operational Basis; Global Skyrizi Net Revenues Were $3.425 Billion ; Global Rinvoq Net Revenues Were $1.718 Billion ; Global Humira Net Revenues Were $1.121 Billion
First-Quarter Global Net Revenues from the Neuroscience Portfolio Were $2.282 Billion , an Increase of 16.1 Percent on a Reported Basis, or 17.0 Percent on an Operational Basis; Global Vraylar Net Revenues Were $765 Million ; Global Botox Therapeutic Net Revenues Were $866 Million ; Combined Global Ubrelvy and Qulipta Net Revenues Were $433 Million
First-Quarter Global Net Revenues from the Oncology Portfolio Were $1.633 Billion , an Increase of 5.8 Percent on a Reported Basis, or 7.5 Percent on an Operational Basis; Global Imbruvica Net Revenues Were $738 Million ; Global Venclexta Net Revenues Were $665 Million ; Global Elahere Net Revenues Were $179 Million
First -Quarter Global Net Revenues from the Aesthetics Portfolio Were $1.102 Billion , a Decrease of 11.7 Percent on a Reported Basis, or 10.2 Percent on an Operational Basis; Global Botox Cosmetic Net Revenues Were $556 Million ; Global Juvederm Net Revenues Were $231 Million
Raises 2025 Adjusted Diluted EPS Guidance Range from $11.99 - $12.19 to $12.09 - $12.29 , which Includes an Unfavorable Impact of $0.13 Per Share Related to Acquired IPR&D and Milestones Expense Incurred Year-To-Date Through the First Quarter 2025

- AbbVie (NYSE:ABBV) announced financial results for the first quarter ended March 31, 2025 .

"AbbVie's first-quarter results were well ahead of our expectations and reflect an excellent start to the year," said Robert A. Michael , chief executive officer, AbbVie. "The fundamentals of our business are strong and we continue to bolster our outlook with pipeline advancements and strategic investments. Based on the progress we are making, AbbVie is well positioned for the long term."

First -Quarter Results

Worldwide net revenues were $13.343 billion , an increase of 8.4 percent on a reported basis, or 9.8 percent on an operational basis.
Global net revenues from the immunology portfolio were $6.264 billion , an increase of 16.6 percent on a reported basis, or 18.1 percent on an operational basis.
- Global Skyrizi net revenues were $3.425 billion , an increase of 70.5 percent on a reported basis, or 72.0 percent on an operational basis.
- Global Rinvoq net revenues were $1.718 billion , an increase of 57.2 percent on a reported basis, or 59.7 percent on an operational basis.
- Global Humira net revenues were $1.121 billion , a decrease of 50.6 percent on a reported basis, or 49.5 percent on an operational basis.
Global net revenues from the neuroscience portfolio were $2.282 billion , an increase of 16.1 percent on a reported basis, or 17.0 percent on an operational basis.
- Global Vraylar net revenues were $765 million , an increase of 10.3 percent.
- Global Botox Therapeutic net revenues were $866 million , an increase of 15.8 percent on a reported basis, or 17.0 percent on an operational basis.
- Global Ubrelvy net revenues were $240 million , an increase of 17.8 percent on a reported basis, or 18.0 percent on an operational basis.
- Global Qulipta net revenues were $193 million , an increase of 47.6 percent on a reported basis, or 48.3 percent on an operational basis.
Global net revenues from the oncology portfolio were $1.633 billion , an increase of 5.8 percent on a reported basis, or 7.5 percent on an operational basis.
- Global Imbruvica net revenues were $738 million , a decrease of 11.9 percent.
- Global Venclexta net revenues were $665 million , an increase of 8.3 percent on a reported basis, or 12.3 percent on an operational basis.
- Global Elahere net revenues were $179 million .
Global net revenues from the aesthetics portfolio were $1.102 billion , a decrease of 11.7 percent on a reported basis, or 10.2 percent on an operational basis.
- Global Botox Cosmetic net revenues were $556 million , a decrease of 12.3 percent on a reported basis, or 10.7 percent on an operational basis.
- Global Juvederm net revenues were $231 million , a decrease of 22.2 percent on a reported basis, or 20.0 percent on an operational basis.
On a GAAP basis, gross margin in the first quarter was 70.0 percent. The adjusted gross margin was 84.1 percent.
On a GAAP basis, selling, general and administrative (SG&A) expense was 24.7 percent of net revenues. The adjusted SG&A expense was 24.6 percent of net revenues.
On a GAAP basis, research and development (R&D) expense was 15.5 percent of net revenues. The adjusted R&D expense was 15.4 percent of net revenues.
Acquired IPR&D and milestones expense was 1.9 percent of net revenues.
On a GAAP basis, operating margin in the first quarter was 28.0 percent. The adjusted operating margin was 42.3 percent.
Net interest expense was $627 million .
On a GAAP basis, the tax rate in the quarter was 22.4 percent. The adjusted tax rate was 14.2 percent.
Diluted EPS in the first quarter was $0.72 on a GAAP basis. Adjusted diluted EPS, excluding specified items, was $2.46 . These results include an unfavorable impact of $0.13 per share related to acquired IPR&D and milestones expense.

Note: "Operational" comparisons are presented at constant currency rates that reflect comparative local currency net revenues at the prior year's foreign exchange rates.

Recent Events

AbbVie announced that its board of directors unanimously elected chief executive officer (CEO) Robert A. Michael to assume the additional position of chairman of the board of directors, effective July 1, 2025 . He will succeed Richard A. Gonzalez , who formerly served as AbbVie's CEO and has been chairman since the Company's formation in 2013.
AbbVie announced that the European Commission (EC) granted marketing authorization to Rinvoq (upadacitinib) for the treatment of giant cell arteritis (GCA) in adult patients. The approval was supported by data from the pivotal Phase 3 SELECT-GCA trial which demonstrated that Rinvoq achieved the primary endpoint of sustained remission and key secondary endpoints, including reduction in disease flares, lower cumulative steroid exposure and complete remission. This authorization marks the eighth approved indication for Rinvoq in the European Union (EU).
At the Society of Gynecologic Oncology (SGO) Annual Meeting, AbbVie announced final data analysis from the Phase 3 MIRASOL trial evaluating the efficacy and safety of Elahere (mirvetuximab soravtansine-gynx) in women with folate receptor alpha (FRα)-positive platinum-resistant ovarian cancer (PROC) compared to chemotherapy. At 30.5 months median follow-up, treatment with Elahere continued to show significant improvements in progression-free survival (PFS) and overall survival (OS) compared to investigator's choice (IC) chemotherapy.
AbbVie and Xilio Therapeutics, a clinical-stage biotechnology company, announced a collaboration and option-to-license agreement that will combine AbbVie's oncology expertise with Xilio's proprietary tumor-activation technology to develop novel immunotherapies, including masked T-cell engagers, for people living with cancer.
AbbVie announced that it submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of trenibotulinumtoxinE (BoNT/E) for the treatment of moderate to severe glabellar lines. TrenibotulinumtoxinE is a first-in-class botulinum neurotoxin serotype E characterized by a rapid onset of action as early as 8 hours after administration and short duration of effect of 2-3 weeks. If approved, trenibotulinumtoxinE will be the first neurotoxin of its kind available to patients.
Allergan Aesthetics announced that the Allergan Medical Institute (AMI) will open three new state-of-the-art training centers in the U.S., expanding access to high-quality, tailored training for licensed aesthetics providers. The first training center is scheduled to open in Irvine, CA , with additional locations to follow in Atlanta, GA and Austin, TX.
AbbVie and Gubra announced a license agreement to develop GUB014295 (ABBV-295), a potential best-in-class, long-acting amylin analog for the treatment of obesity. This partnership marks AbbVie's entrance into the obesity field and under the terms of the agreement, AbbVie will lead development and commercialization of GUB014295 globally. Prior to the close of the agreement, Gubra announced positive interim results from Part A of a Phase 1 multiple ascending dose (MAD) study, which showed that GUB014295 was well tolerated with body weight loss that was sustained in a manner consistent with data from a previously announced single ascending dose (SAD) study.
AbbVie announced that the FDA approved Emblaveo (aztreonam and avibactam), as the first monobactam/β-lactamase inhibitor combination antibiotic therapy to treat complicated intra-abdominal infections, including those caused by Gram-negative bacteria. The approval of Emblaveo was supported by prior findings regarding the efficacy and safety of aztreonam for the treatment of complicated intra-abdominal infections as well as clinical trial results from the Phase 3 REVISIT study, which evaluated the efficacy, safety, and tolerability of Emblaveo for the treatment of serious infections due to Gram-negative bacteria.

Full-Year 2025 Outlook

AbbVie is raising its adjusted diluted EPS guidance for the full year 2025 from $11.99 - $12.19 to $12.09 - $12.29 , which includes an unfavorable impact of $0.13 per share related to acquired IPR&D and milestones expense incurred year-to-date through the first quarter 2025. The company's 2025 adjusted diluted EPS guidance excludes any impact from acquired IPR&D and milestones that may be incurred beyond the first quarter of 2025, as both cannot be reliably forecasted. This guidance does not reflect the acquired IPR&D and milestones impact related to AbbVie and Gubra's licensing agreement to develop GUB014295, as that transaction closed after the first quarter of 2025. Additionally, this guidance is based on the existing trade environment and does not reflect any trade policy shifts, including pharmaceutical sector tariffs, that could impact AbbVie's business.

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, neuroscience, oncology, and eye care - and products and services across our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X (formerly Twitter), Facebook , Instagram , YouTube or LinkedIn .

Conference Call

AbbVie will host an investor conference call today at 8:00 a.m. Central Time to discuss our first-quarter performance. The call will be webcast through AbbVie's Investor Relations website at investors.abbvie.com . An archived edition of the call will be available after 11:00 a.m. Central Time .

Non-GAAP Financial Results

Financial results for 2025 and 2024 are presented on both a reported and a non-GAAP basis. Reported results were prepared in accordance with GAAP and include all revenue and expenses recognized during the period. Non-GAAP results adjust for certain non-cash items and for factors that are unusual or unpredictable, and exclude those costs, expenses, and other specified items presented in the reconciliation tables later in this release. AbbVie's management believes non-GAAP financial measures provide useful information to investors regarding AbbVie's results of operations and assist management, analysts, and investors in evaluating the performance of the business. Non-GAAP financial measures should be considered in addition to, and not as a substitute for, measures of financial performance prepared in accordance with GAAP.

Forward-Looking Statements

Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry, the impact of global macroeconomic factors, such as economic downturns or uncertainty, international conflict, trade disputes and tariffs, and other uncertainties and risks associated with global business operations. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2024 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its Quarterly Reports on Form 10-Q and in other documents that AbbVie subsequently files with the Securities and Exchange Commission that update, supplement or supersede such information. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law.

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AbbVie Inc. Key Product Revenues Quarter Ended March 31, 2025 (Unaudited)

				% Change vs. 1Q24
	Net Revenues (in millions)			Reported			Operational ^a
	U.S.	Int'l.	Total	U.S.	Int'l.	Total	Int'l.	Total
NET REVENUES	$9,979	$3,364	$13,343	10.4 %	2.9 %	8.4 %	8.3 %	9.8 %

Immunology	4,883	1,381	6,264	17.6	13.4	16.6	20.1	18.1
Skyrizi	2,919	506	3,425	76.2	43.9	70.5	52.3	72.0
Rinvoq	1,220	498	1,718	68.3	35.3	57.2	42.8	59.7
Humira	744	377	1,121	(58.0)	(24.4)	(50.6)	(19.5)	(49.5)

Neuroscience	1,972	310	2,282	15.0	24.0	16.1	31.0	17.0
Vraylar	763	2	765	10.3	13.1	10.3	20.2	10.3
Botox Therapeutic	723	143	866	18.2	4.8	15.8	11.4	17.0
Ubrelvy	233	7	240	17.6	23.3	17.8	29.3	18.0
Qulipta	172	21	193	34.2	>100.0	47.6	>100.0	48.3
Vyalev	6	57	63	n/m	>100.0	>100.0	>100.0	>100.0
Duodopa	20	76	96	(19.4)	(16.0)	(16.7)	(11.7)	(13.3)
Other Neuroscience	55	4	59	(9.5)	(1.0)	(8.9)	6.5	(8.4)

Oncology	1,027	606	1,633	6.0	5.4	5.8	10.0	7.5
Imbruvica ^b	529	209	738	(13.3)	(8.2)	(11.9)	(8.2)	(11.9)
Venclexta	312	353	665	11.0	6.0	8.3	13.4	12.3
Elahere	165	14	179	>100.0	n/m	>100.0	n/m	>100.0
Epkinly ^c	21	30	51	66.7	>100.0	89.8	>100.0	94.8

Aesthetics	640	462	1,102	(17.4)	(2.4)	(11.7)	1.6	(10.2)
Botox Cosmetic	295	261	556	(24.3)	6.9	(12.3)	11.1	(10.7)
Juvederm Collection	75	156	231	(29.0)	(18.5)	(22.2)	(15.0)	(20.0)
Other Aesthetics	270	45	315	(3.5)	18.1	(0.9)	23.2	(0.3)

Eye Care	221	285	506	(2.6)	(8.0)	(5.7)	(2.0)	(2.2)
Ozurdex	30	93	123	(12.1)	(3.8)	(6.0)	1.1	(2.4)
Lumigan/Ganfort	48	58	106	69.2	(6.8)	17.0	(0.5)	21.4
Alphagan/Combigan	26	34	60	68.5	(21.4)	1.9	(15.4)	6.3
Other Eye Care	117	100	217	(21.4)	(7.1)	(15.4)	(0.2)	(12.5)

Other Key Products	636	173	809	(7.2)	(19.4)	(10.1)	(14.8)	(9.0)
Mavyret	142	164	306	(0.7)	(20.4)	(12.3)	(15.8)	(9.6)
Creon	355	—	355	24.6	n/m	24.6	n/m	24.6
Linzess/Constella	139	9	148	(46.1)	3.1	(44.4)	9.3	(44.2)


^a	"Operational" comparisons are presented at constant currency rates that reflect comparative local currency net revenues at the prior year's foreign exchange rates.
^b	Reflects profit sharing for Imbruvica international revenues.
^c	Epkinly U.S. revenues reflect profit sharing. International revenues reflect product revenues as well as profit sharing from certain international territories.
n/m = not meaningful

AbbVie Inc. Consolidated Statements of Earnings (Unaudited)

(in millions, except per share data)	First Quarter Ended March 31
	2025	2024
Net revenues	{replace1}nbsp; 13,343	{replace1}nbsp; 12,310
Cost of products sold	4,002	4,094
Selling, general and administrative	3,293	3,315
Research and development	2,067	1,939
Acquired IPR&D and milestones	248	164
Total operating costs and expenses	9,610	9,512

Operating earnings	3,733	2,798

Interest expense, net	627	453
Net foreign exchange loss	4	4
Other expense, net	1,441	586
Earnings before income tax expense	1,661	1,755
Income tax expense	372	383
Net earnings	1,289	1,372
Net earnings attributable to noncontrolling interest	3	3
Net earnings attributable to AbbVie Inc.	{replace1}nbsp; 1,286	{replace1}nbsp; 1,369

Diluted earnings per share attributable to AbbVie Inc.	{replace1}nbsp; 0.72	{replace1}nbsp; 0.77

Adjusted diluted earnings per share ^a	{replace1}nbsp; 2.46	{replace1}nbsp; 2.31

Weighted-average diluted shares outstanding	1,772	1,773


^a	Refer to the Reconciliation of GAAP Reported to Non-GAAP Adjusted Information for further details.

AbbVie Inc. Reconciliation of GAAP Reported to Non-GAAP Adjusted Information (Unaudited)

1. Specified items impacted results as follows:

	Quarter Ended March 31, 2025
(in millions, except per share data)	Earnings		Diluted
	Pre-tax	After-tax ^a	EPS
As reported (GAAP)	{replace1}nbsp; 1,661	{replace1}nbsp; 1,286	{replace1}nbsp; 0.72
Adjusted for specified items:
Intangible asset amortization	1,858	1,574	0.89
Change in fair value of contingent consideration	1,518	1,477	0.83
Other	62	33	0.02
As adjusted (non-GAAP)	{replace1}nbsp; 5,099	{replace1}nbsp; 4,370	{replace1}nbsp; 2.46

^a Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.

Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2025 included acquired
IPR&D and milestones expense of $248 million on a pre-tax and $238 million on an after-tax basis, representing an
unfavorable impact of $0.13 to both diluted EPS and adjusted diluted EPS.

2. The impact of the specified items by line item was as follows:

	Quarter Ended March 31, 2025
(in millions)	Cost of products sold	SG&A	R&D	Other expense, net
As reported (GAAP)	{replace1}nbsp; 4,002	{replace1}nbsp; 3,293	{replace1}nbsp; 2,067	{replace1}nbsp; 1,441
Adjusted for specified items:
Intangible asset amortization	(1,858)	—	—	—
Change in fair value of contingent consideration	—	—	—	(1,518)
Other	(28)	(13)	(16)	(5)
As adjusted (non-GAAP)	{replace1}nbsp; 2,116	{replace1}nbsp; 3,280	{replace1}nbsp; 2,051	{replace1}nbsp; (82)


3. The adjusted tax rate for the first quarter of 2025 was 14.2 percent, as detailed below:

	Quarter Ended March 31, 2025
(dollars in millions)	Pre-tax earnings	Income taxes	Tax rate
As reported (GAAP)	{replace1}nbsp; 1,661	{replace1}nbsp; 372	22.4 %
Specified items	3,438	354	10.3 %
As adjusted (non-GAAP)	{replace1}nbsp; 5,099	{replace1}nbsp; 726	14.2 %

AbbVie Inc. Reconciliation of GAAP Reported to Non-GAAP Adjusted Information (Unaudited)

1. Specified items impacted results as follows:

	Quarter Ended March 31, 2024
(in millions, except per share data)	Earnings		Diluted
	Pre-tax	After-tax ^a	EPS
As reported (GAAP)	{replace1}nbsp; 1,755	{replace1}nbsp; 1,369	{replace1}nbsp; 0.77
Adjusted for specified items:
Intangible asset amortization	1,891	1,603	0.90
Acquisition and integration costs	511	486	0.27
Change in fair value of contingent consideration	660	643	0.36
Other	21	19	0.01
As adjusted (non-GAAP)	{replace1}nbsp; 4,838	{replace1}nbsp; 4,120	{replace1}nbsp; 2.31

^a Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.

Acquisition and integration costs primarily reflect costs related to the ImmunoGen acquisition.

Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2024 included acquired
IPR&D and milestones expense of $164 million on a pre-tax and $138 million on an after-tax basis, representing an
unfavorable impact of $0.08 to both diluted EPS and adjusted diluted EPS.

2. The impact of the specified items by line item was as follows:

	Quarter Ended March 31, 2024
(in millions)	Cost of products sold	SG&A	R&D	Interest expense, net	Other expense, net
As reported (GAAP)	{replace1}nbsp; 4,094	{replace1}nbsp; 3,315	{replace1}nbsp; 1,939	{replace1}nbsp; 453	{replace1}nbsp; 586
Adjusted for specified items:
Intangible asset amortization	(1,891)	—	—	—	—
Acquisition and integration costs	(79)	(280)	(128)	(24)	—
Change in fair value of contingent consideration	—	—	—	—	(660)
Other	(16)	(3)	—	—	(2)
As adjusted (non-GAAP)	{replace1}nbsp; 2,108	{replace1}nbsp; 3,032	{replace1}nbsp; 1,811	{replace1}nbsp; 429	{replace1}nbsp; (76)


3. The adjusted tax rate for the first quarter of 2024 was 14.8 percent, as detailed below:

	Quarter Ended March 31, 2024
(dollars in millions)	Pre-tax earnings	Income taxes	Tax rate
As reported (GAAP)	{replace1}nbsp; 1,755	{replace1}nbsp; 383	21.8 %
Specified items	3,083	332	10.8 %
As adjusted (non-GAAP)	{replace1}nbsp; 4,838	{replace1}nbsp; 715	14.8 %

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Accent Trial Data Demonstrates that Narmafotinib + Chemotherapy Combination Superior to Chemotherapy Alone

Amplia Therapeutics Limited (ASX: ATX), (“Amplia” or the “Company”), is pleased to announce important new data from our ongoing ACCENT clinical trial in pancreatic cancer. The trial is investigating the Company’s best-in-class FAK inhibitor narmafotinib in combination with standard-of-care chemotherapies gemcitabine and Abraxane. Fifteen (15) confirmed partial responses (PRs) have now been recorded in the trial, a level of response sufficient to demonstrate that the combination of narmafotinib and chemotherapy is superior to chemotherapy alone.

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BOTOX® Cosmetic Continues its Mission of Empowering Entrepreneurs Through "The Confidence Project"

BOTOX ^® Cosmetic Will Provide 250 Entrepreneurs with Access to New Resources and Opportunities and Will Award 20 Grants Worth $20,000 Each to Support Business Goals.
By 2030, BOTOX ^® Cosmetic Pledges to Empower 50,000 Entrepreneurs, Helping to Close the Confidence Gap.

- Allergan Aesthetics, an AbbVie company (NYSE: ABBV), today announced BOTOX ® Cosmetic's continued commitment to closing the Confidence Gap with the introduction of The Confidence Project: Empowering Women Entrepreneurs . The one & only BOTOX ® Cosmetic invites business owners to apply for this year's program starting today through May 9, 2025 at 11:59pm PT .

Women entrepreneurs continue to break barriers in the business world, with increasing efforts to close the Confidence Gap. When women founders are supported by mentors and have access to capital, they become agents of change. Seventy-one percent of businesswomen said their mentor was influential in their career advancement, with many using their income to uplift their families and community. ¹

Since 2023, BOTOX ^® Cosmetic has provided a total of $1 million dollars in grant funding across more than 40 founders, along with coaching and networking opportunities. This year, BOTOX ^® Cosmetic is expanding to reach more founders by providing 250 entrepreneurs with access to The Confidence Project. Through a partnership with Hello Alice, an online platform that helps businesses launch and grow, each of the 250 entrepreneurs will participate in an intensive "Boostcamp" program, which will provide participants with skill-building, mentorship resources, and exclusive networking opportunities. After completing the course, they will leverage their newfound skills to pitch their business to a panel of aesthetic entrepreneurs, as well as key business leaders from Allergan Aesthetics and Hello Alice, for a chance to receive one of 20 $20,000 grants from BOTOX ^® Cosmetic.

"BOTOX ^® Cosmetic is committed to being a catalyst for confidence, whether that be by pursuing education, aesthetic treatment, or your entrepreneurial goals. Through The Confidence Project, we pledge to continue to uplift founders who've invested so much in their businesses," said Nicole Katz , Vice President, Customer Engagement and Corporate Affairs at Allergan Aesthetics. "We know when women have access to resources and capital, there's no limit to what they can achieve. We look forward to getting to know this year's cohort of founders and how they found the confidence to pursue their dreams."

"Our mission at Hello Alice is to help entrepreneurs access the funding, mentorship, and resources they need to succeed. BOTOX ^® Cosmetic's The Confidence Project provides a powerful opportunity for women entrepreneurs to scale their businesses and create lasting change," said Elizabeth Gore , Co-Founder and President of Hello Alice. "Our partnership with BOTOX ^® Cosmetic aims to foster long-term growth, confidence, and leadership for future generations of women in business, by investing in their success today."

Business owners and their cofounders interested in applying to The Confidence Project are encouraged to visit www.botoxcosmetic.com/realimpact . Applicants must agree to the official rules of the grant program and submissions must be received by May 9, 2025 , at 11:59pm PT . The 250 women entrepreneurs selected to participate in the Hello Alice Boostcamp will be announced in July, and the 20 grant recipients will be announced in October 2025 .

For more information on The Confidence Project, visit www.botoxcosmetic.com/realimpact and follow @botoxcosmetic on Instagram and YouTube .

About Allergan Aesthetics
At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit www.allerganaesthetics.com .

About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn , Facebook , Instagram , X (formerly Twitter) , and YouTube .

Approved Uses
BOTOX ^® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow's feet lines, frown lines between the eyebrows, and vertical bands connecting the jaw and neck (platysma bands) in adults.

IMPORTANT SAFETY INFORMATION

BOTOX ^® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX ^® Cosmetic:

Problems swallowing, speaking, or breathing, due to weakening of associated muscles, which can be severe and result in loss of life. You are at the highest risk if these problems are preexisting before injection. Swallowing problems may last for several months.

Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms, including loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.

BOTOX ^® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product.

There has not been a confirmed serious case of spread of toxin effect when BOTOX ^® Cosmetic has been used at the recommended dose to treat frown lines, crow's feet lines, forehead lines, and/or platysma bands.

BOTOX ^® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of receiving BOTOX ^® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities.

Serious and/or immediate allergic reactions have been reported, including itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.

Do not receive BOTOX ^® Cosmetic if you are allergic to any of the ingredients in BOTOX ^® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc (rimabotulinumtoxinB), Dysport (abobotulinumtoxinA), Xeomin (incobotulinumtoxinA), Jeuveau (prabotulinumtoxinA-xvfs), Daxxify (daxibotulinumtoxinA-lanm), or Letybo (letibotulinumtoxinA-wlbg); or have a skin infection at the planned injection site. This list may not include all available botulinum toxin products.

Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig's disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects, including difficulty swallowing and difficulty breathing, from standard doses of BOTOX ^® Cosmetic.

Tell your doctor about all your medical conditions, including surgery or plans to have surgery on your face, trouble raising your eyebrows, drooping eyelids, any other abnormal facial change, are pregnant or plan to become pregnant (it is not known if BOTOX ^® Cosmetic can harm your unborn baby), or are breastfeeding or plan to (it is not known if BOTOX ^® Cosmetic passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX ^® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX ^® Cosmetic in the past.

Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc, Dysport, Xeomin, Jeuveau, Daxxify, or Letybo in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; or take aspirin-like products or blood thinners.

Other side effects of BOTOX ^® Cosmetic include dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems, including double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of eyelids, and dry eyes.

For more information, refer to the Medication Guide or talk with your doctor.

To report a side effect, please call Allergan Aesthetics at 1-800-678-1605.

Please see BOTOX ^® Cosmetic full Prescribing Information , including Boxed Warning and Medication Guide .

References:

Barbara Kurshan. Forbes.com. Purpose-Driven Women: Unleash Your Potential Through Mentorship. 2023 https://www.forbes.com/sites/barbarakurshan/2023/06/13/purpose-driven-women-unleash-your-potential-through-mentorship/

Contacts:

Investors:
Liz Shea
Liz.Shea@AbbVie.com
(847) 935-2211

Media:
Ember Garrett
Ember.Garrett@allergan.com
(714) 246-3525

View original content to download multimedia: https://www.prnewswire.com/news-releases/botox-cosmetic-onabotulinumtoxina-continues-its-mission-of-empowering-entrepreneurs-through-the-confidence-project-302444121.html

SOURCE AbbVie

News Provided by PR Newswire via QuoteMedia

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Adicet Bio to Participate in a Fireside Chat at the Citizens JMP Life Sciences Conference

Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer, today announced that Chen Schor, President and Chief Executive Officer, will participate in a fireside chat at the 2025 Citizens JMP Life Sciences Conference being held from May 7-8, 2025 in New York.

Details of the event are as follows:
Date: Wednesday, May 7, 2025
Time: 1:30 p.m. ET

News Provided by Business Wire via QuoteMedia

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ADICET BIO, INC. Consolidated Statements of Operations and Comprehensive Income (in thousands, except share and per share amounts) (Unaudited)

	Three Months Ended March 31,
	2025			2024
Operating expenses:
Research and development	$	22,814		$	23,897
General and administrative		7,071			6,974
Total operating expenses		29,885			30,871
Loss from operations		(29,885	)		(30,871	)
Interest income		1,683			2,918
Interest expense		—			(2	)
Other expense, net		(12	)		(61	)
Loss before income tax provision		(28,214	)		(28,016	)
Income tax provision		—			—
Net loss	$	(28,214	)	$	(28,016	)
Net loss per share, basic and diluted	$	(0.31	)	$	(0.35	)
Weighted-average common shares used in computing net loss per share, basic and diluted		91,071,436			79,071,652
Other comprehensive income
Unrealized loss on treasury securities, net of tax		(25	)		—
Total other comprehensive income		(25	)		—
Comprehensive loss	$	(28,239	)	$	(28,016	)

ADICET BIO, INC. Consolidated Balance Sheets Information (in thousands) (Unaudited)

	March 31,			December 31,
	2025				2024
Cash, cash equivalents, and short term investments in treasury securities	$	150,439			$	176,303
Working capital		137,116				160,744
Total assets		191,271				220,219
Accumulated deficit		(526,108	)			(497,894	)
Total stockholders' equity		161,446				186,609

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