Isodiol International Inc. (CSE:ISOL) (OTC:ISOLF) (FSE:LB6A.F) (the “Company” or “Isodiol”), a global bioactive phytoceutical innovator specializing in the development of pharmaceutical and wellness products, announced today that it has signed a Letter of Intent to acquire 100% of the CBD assets of Green Island Naturals.
Green Island Naturals is a formulator, marketer and seller of a proprietary line of hemp extract products that are distributed in retail and online channels in Canada. By combining science with a deep understanding of traditional plant based medicines, Green Island Naturals produces innovative products designed to improve and diversify treatment options for the consumers. In 2017 revenues exceed over $2,000,000 and the Company anticipate this to grow exponentially in 2018 with the support of Isodiol’s family of brands.
“Isodiol and the Green Island Naturals brand share a mutual goal of providing consumers with high-quality Cannabinoid products that promote both physical and mental well-being, making this partnership an easy decision,” said Marcos Agramont, CEO of Isodiol. “This acquisition also allows us to diversify our product offerings, expand our distribution partners, and remain leaders in product innovation. Isodiol is growing at a rapid pace; in addition to the increase of revenue this partnership will bring, it has also enabled us to partner with some of the best medical experts in the sector.”
Green Island Naturals’ product offerings include solvent-free and low-solvent tinctures that can be placed under the tongue, eaten, or used topically. Made with high grade-concentrates that are lab-tested for accurate dosing, these tinctures boast great potency and set the standard for consistent quality. For a complete list of current product offerings visit https://greenislandnaturals.ca/.
As part of this agreement, Isodiol will issue Green Island Naturals, up to CAD$2,000,000 in Isodiol Shares subject to standard CSE guidelines. Additional information will be provided upon execution of the definitive agreement in the coming weeks.
For more information on Isodiol, please visit www.isodiol.com
For more information on Green Island Naturals, please visit www.greenislandnaturals.ca
About Isodiol International Inc.
Isodiol International Inc. is the market leader in pharmaceutical grade phytochemical compounds and the industry leader in the manufacturing and development of phytoceutical consumer products.
Isodiol is the pioneer of many firsts for the cannabis industry including commercialization of 99%+ pure, bioactive pharmaceutical grade cannabinoids, micro-encapsulations, and nanotechnology for the highest quality consumable and topical skin care products.
Isodiol’s growth strategy includes the development of over-the-counter and pharmaceutical drugs, expanding its phytoceutical portfolio and will aggressively continue international expansion into Latin America, Asia and Europe.
Join Us On Facebook: https://www.facebook.com/isodiol/
Twitter:@isodiol
ON BEHALF OF THE BOARD
Marcos Agramont, CEO & Director
604-409-4409
marcos@isodiol.com
INVESTOR RELATIONS:
Ir@isodiol.com
www.isodiol.com
MEDIA CONTACT:
Carrie Booze
North 6th Agency
212-334-9753 ext.142
Isodiol@n6a.com
Forward-Looking Information:This news release contains “forward-looking information” within the meaning of applicable securities laws relating to statements regarding the Company’s business, products and future of the Company’s business, its product offerings and plans for sales and marketing. Although the Company believes that the expectations reflected in the forward-looking information are reasonable, there can be no assurance that such expectations will prove to be correct. Readers are cautioned to not place undue reliance on forward-looking information. Such forward looking statements are subject to risks and uncertainties that may cause actual results, performance and developments to differ materially from those contemplated by these statements depending on, among other things, the risks that the Company’s products and plan will vary from those stated in this news release and the Company may not be able to carry out its business plans as expected. Except as required by law, the Company expressly disclaims any obligation, and does not intend, to update any forward-looking statements or forward-looking information in this news release. Although the Company believes that the expectations reflected in the forward-looking information are reasonable, there can be no assurance that such expectations will prove to be correct and makes no reference to profitability based on sales reported. The statements in this news release are made as of the date of this release.
The CSE has not reviewed, approved or disapproved the content of this press release.
Click here to connect with Isodiol International Inc. (CSE:ISOL) to receive an Investor Presentation

Source: globenewswire.com


NanoSphere Health Sciences Inc. (CSE:NSHS) (“NanoSphere”) is pleased to announce that it has been nominated for the National Cannabis Industry Association’s Excellence in Technology Award in Infused Products and Extraction. This award goes to a NCIA member who has developed new technology that will have a lasting impact on the industry. Also, effective today, NanoSphere’s OTC ticker code NSHSF has been approved for use.
“It comes as no surprise to us that our technology is being recognized for its market disruption,” said Dr. Richard Kaufman, Chief Science Officer at NanoSphere. “We are proud of our achievements so far in the nanoparticle delivery space and look forward to advancing our technology with new applications and new markets.”
NanoSphere is commercializing its disruptive, next-generation nanoparticle cannabis delivery system platforms under the brand Evolve Formulas. In July 2017, Evolve launched its acclaimed NanoSerum™ product for the recreational and medical cannabis markets in Colorado. NanoSerum™, which has made major market inroads in less than six months of sale, is the first clinically tested transdermal cannabis product to relieve pain in minutes.
NanoSphere Chairman and CEO Robert Sutton added, “As our company is opened to the investor marketplace, more and more consumers will discover our technology. The re-order rate of our NanoSerum product is testament to its quality and effectiveness.”
The award-winning Evolve is available in over 70 accounts throughout Colorado. NanoSphere expects to expand its fast-growing network with manufacturers and operators in several states to license our technology and bring the Evolve brand to new U.S. markets, and to build on that success by further introducing new product applications. Each product application will deliver a unique pharmacokinetic and pharmacodynamic profile of cannabinoid activity and therapeutic applications.
About NanoSphere
NanoSphere Health Sciences LLC, a wholly owned operating subsidiary of the Company, is a biotechnology firm specializing in the creation of the NanoSphere Delivery System™, a revolutionary platform using nanotechnology in the biodelivery of supplements, nutraceuticals and over-the-counter medications for the cannabis, pharmaceutical and animal health industries, and beyond. The patent-pending NanoSphere Delivery System™ represents one of the most important developments for advancing the non-invasive and user-friendly delivery of biological agents in over 25 years. For more information on NanoSphere, please visit http://www.nanospherehealth.com.
On behalf of the Board
David Sutton, President and COO
720.520.4283
dsutton@nanospherehealth.com
PR Contact:
Kate Wells, Chief Marketing Officer
NanoSphere Health Sciences, LLC
Direct: 720-528-4437
Mobile: 303-324-7358
E-mail: kwells@nanospherehealth.com
Investor Contact:
Victor Goncalves, Executive Vice President
Mobile: 204-997-5517
E-mail: vgoncalves@nanospherehealth.com
The Canadian Securities Exchange does not accept responsibility for the adequacy or accuracy of this release.
Forward Looking Statement Caution
This news release includes forward looking statements that are subject to assumptions, risks and uncertainties. Statements in this news release which are not purely historical are forward looking statements, including without limitation any statements concerning the Company’s intentions, plans, estimates, expectations or beliefs regarding the future. Although the Company believes that any forward looking statements in this news release are reasonable, there can be no assurance that any such forward looking statements will prove to be accurate. The Company cautions readers that all forward looking statements, including without limitation those relating to the Company’s future operations and business prospects, are based on assumptions none of which can be assured, and are subject to certain risks and uncertainties that could cause actual events or results to differ materially from those indicated in the forward looking statements. Readers are advised to rely on their own evaluation of such risks and uncertainties and should not place undue reliance on forward looking statements. Any forward looking statements are made as of the date of this news release, and the Company assumes no obligation to update the forward looking statements, or to update the reasons why actual events or results could or do differ from those projected in the forward looking statements, whether as a result of new information, future events or otherwise.
Click here to connect with NanoSphere Health Sciences Inc. (CSE:NSHS) to receive an Investor Presentation

Source: globenewswire.com


Cardiol Therapeutics Inc. (“Cardiol” or the “Company”), a nanotherapeutics company focused on the research and commercial development of proprietary drug formulations for the treatment of heart failure, is pleased to announce that experimental research performed at the Houston Methodist DeBakey Heart & Vascular Center, Texas, shows new functionality of the Company’s patented nanotherapeutics. Designed to act as a vehicle to target anti-inflammatory drugs to inflamed heart tissue, these new data demonstrate the accumulation of nanoparticles at regions of fibrosis in diseased hearts, showing potential for Cardiol’s proprietary nanotechnology to be used to target anti-fibrotic drugs directly to areas of fibrosis to treat heart failure.
Researchers at the Houston Methodist DeBakey Heart & Vascular Center administered fluorescently-labelled Cardiol nanoparticles to an experimental model of heart failure. Bright fluorescence was observed in heart failure cardiac tissue, whereas no significant fluorescence was seen in control hearts, showing preferential accumulation of nanoparticles in failing hearts. Importantly, the highest concentrations of fluorescent nanoparticles were seen localized within non-contractile cells in areas of fibrous tissue within the heart – these primarily spindle-shaped cells associated with areas of fibrosis are considered to be fibroblasts (the cells responsible for fibrosis).
“These research results provide new insight into how our nanotherapeutics can be developed to target fibrous tissue in the heart and are the subject of our comprehensive provisional patent application recently filed in the United States,” said David Elsley, President and CEO of Cardiol Therapeutics. “The specific targeting of our nanoparticles to cardiac fibrous tissue offers the potential to utilize drugs more safely and effectively and suggests the possibility of preventing the progression of cardiac fibrosis.”
Inflammation is one of the earliest precursors to fibrosis, a pathology associated with heart disease. Associated with the infiltration of activated inflammatory immune cells into the heart, inflammation leads to the inappropriate activation of fibrocytes into myofibroblasts – the cell type responsible for the deposition of inflexible fibrous material that causes fibrosis. Fibrotic cardiac tissue does not contract and is stiffer than normal, leading to the loss of chamber distensibility that is a common feature of heart failure. These research data show the promise of a new way to target anti-inflammatory and anti-fibrotic drugs directly to the regions of the heart where they will be most effective.
“Fibrosis is a key player in the progression of heart failure with preserved ejection fraction (HFpEF), a chronic condition for which there have been no meaningful advances in treatment in over 20 years,” said Dr. Guillermo Torre-Amione, President of TecSalud, Mexico, former Chief of the Heart Failure Division and Medical Director of Cardiac Transplantation at the Houston Methodist DeBakey Heart & Vascular Center, and a member of Cardiol’s Scientific Advisory Board. “These findings represent a new way to address this vastly underserved segment of the heart failure market by delivering effective therapy to inflamed tissue in the heart.”
About Cardiol Therapeutics
Cardiol Therapeutics is a nanotherapeutics company focused on the research and commercial development of proprietary drug formulations for the treatment of heart failure. Heart failure is a chronic condition that affects more than 26 million people globally. Over five million adults in the U.S. suffer from heart failure, and it remains a leading cause of death and hospitalization with associated healthcare costs exceeding $30 billion annually. People with heart failure experience shortness of breath, fatigue, rapid heart rate, edema, reduced exercise capacity and a marked reduction in quality of life. Approximately half of all heart failure patients have heart failure with preserved ejection fraction (HFpEF), which is often associated with diabetes, obesity, and high blood pressure and for which there have been no new therapies developed in over 20 years. Cardiol is developing proprietary nanoformulations of pharmaceutical cannabidiol (CTX01) and methotrexate (CTX02) to target these drugs to the failing heart. Cardiol’s CTX01 is designed to target cannabidiol to areas of inflammation in the hearts of patients with HFpEF. Cannabidiol has been shown to attenuate cardiac dysfunction in experimental diabetic cardiomyopathy and to decrease oxidative stress, fibrosis, and inflammation in additional models relevant to HFpEF. CTX02 is being developed to target methotrexate to areas of cardiac fibrosis in heart failure. Experimental data have shown that Cardiol’s proprietary nanoparticles accumulate within fibrotic areas of the failing heart and that methotrexate has potent anti-fibrotic properties.
For further information, please visit www.cardiolrx.com.
For further information, please contact:
Cardiol Therapeutics Inc.
David Elsley, President & CEO
905.491.6793
david.elsley@cardioltherapeutics.com
Investor Relations:
Trevor Burns
905.491.6793
trevor.burns@cardioltherapeutics.com
Cautionary statement regarding forwardlooking information
This news release contains “forward-looking information” within the meaning of applicable Canadian securities laws which may include but is not limited to statements with respect to the intended business strategy of Cardiol Therapeutics Inc. (“Cardiol”), the potential for Cardiol’s licensed nanoscale drug encapsulation and delivery technologies to enhance the bioavailability of cannabinoids and other drugs. All statements, other than statements of historical fact, that address activities, events or developments that Cardiol believes, expects or anticipates will, may, could or might occur in the future are “forward-looking information”. Forward-looking information is frequently characterized by words such as “plan”, “expect”, “project”, “intend”, “believe”, “anticipate”, “forecast”, and other similar words or statements that certain events or conditions “may” or “will” occur. Forward-looking information reflects the current expectation or beliefs of Cardiol based on information currently available to Cardiol and is subject to a variety of risks and uncertainties and other factors that could cause the actual events or results to differ materially from those discussed in the forward-looking information. These risks, uncertainties and other factors include the inherent risks involved in government approval or no approval in the foreseeable future; the possibility of project cost overruns or unanticipated costs and expenses; unforeseeable deficiencies in the development of the technology; uncertainties relating to the availability and costs of financing needed in the future; Cardiol’s ability to manage growth in its business; competition; failure of clinical trials to demonstrate acceptable levels of safety and efficacy; Cardiol’s ability to retain key management and other personnel; and other risks, uncertainties and factors. These risks, uncertainties and other factors should be considered carefully, and investors should not place undue reliance on the forward-looking information.  Any forward-looking information speaks only as of the date on which it is made and, except as may be required by applicable securities laws, Cardiol disclaims any intent or obligation to update any forward-looking information, whether as a result of new information, future events or results or otherwise.
Click here to connect with Cardiol Therapeutics Inc.

Subsequent to this press release, Cardiol Therapeutics went public on December 20, 2018 under the ticker symbol TSX:CRDL.

Source: www.4-traders.com


MMJ PhytoTech Limited (ASX:MMJ) (“MMJ” or “the Company”) is pleased to advise that its partly-owned TSX-V listed subsidiary, Harvest One Cannabis Inc. (TSXV:HVT) (“Harvest One”), has released two announcements regarding its intentions to undertake a fully underwritten short form prospectus offer to raise up to $25,000,000 initially and then subsequently increased to $35,000,000 (excluding over-allotments) due to strong investor demand.
About Harvest One Cannabis Inc. 
Harvest One Cannabis Inc. (CVE:HVST) controls operations across the entire cannabis value chain through three business units, with Harvest One serving as the umbrella company over horticultural arm United Greeneries and medical arm Satipharm AG. Each business is strategically located in favourable jurisdictions with supportive regulatory frameworks in place. United Greeneries has received a Canadian medicinal cannabis cultivation licence, making Harvest One one of only a few companies globally with the capacity to commercially cultivate cannabis in a federally regulated environment.
To view full copies of the Harvest One announcements, please visit:
http://abnnewswire.net/lnk/S81K7UZ1 
About MMJ PhytoTech Ltd:
MMJ PhytoTech Limited (ASX:MMJ) is focused on becoming a large-scale cannabis producer, targeting direct supply to the growing Canadian medical and recreational markets which will have an estimated combined value of C$8-9 billion by 2024.
The Company controls operations across the entire medicinal cannabis value chain through its ~59% interest in TSX-V listed Harvest One Cannabis Inc (CVE:HVST) and its 100% interest in Israeli research and development subsidiary, PhytoTech Therapeutics Ltd, both of which are strategically located in favourable jurisdictions with supportive regulatory frameworks in place.
Contact:
Andreas Gedeon
Managing Director
Phone: +1-250-713-6302
Email: agedeon@mmj.ca
www.mmjphytotech.com.au
Click here to connect with Harvest One Cannabis Inc. (CVE:HVT) to receive an Investor Presentation

Source: www.abnnewswire.net


Isodiol International Inc. (CSE:ISOL) (OTC:ISOLF) (FSE:LB6A.F) (the “Company” or “Isodiol”), a global bioactive phytoceutical innovator specializing in the development of pharmaceutical and wellness products, is pleased to announce Be Trū Organics™ has signed a distribution agreement with United Natural Foods Inc (UNFI), the largest publicly traded wholesale distributor to the natural, organic and specialty industry in the United States and Canada.
With their distribution centers in the US and Canada, UNFI excels in the distribution of natural and organic foods and wellness products by fulfilling the highest standards for quality, consistency, product assortments, and dependability. Specifically, UNFI provides and delivers products for grocery, produce, health and beauty, bakery, and more.
“UNFI been recognized as one of America’s best managed companies, and with the continuous growth in the natural product industry, we are very excited about the opportunities this presents for Be Trū,” said CEO of Isodiol, Marcos Agramont. “UNFI has a very diversified sales base including natural product superstores, conventional supermarket chains, and independent health food retailers, giving consumers plenty of access to Be Trū products.”
“UNFI’s track record speaks for itself, and we are very pleased to be moving forward with this distribution agreement,” added Keith Gordon, CEO of Be Trū. “UNFI will be instrumental in introducing this brand to mainstream America and will allow Be Trū to continue growing and we look forward to the additional opportunities this agreement will present.”
For more information on Isodiol, please visit www.isodiol.com
For more information on Be Trū Organics™, please visit www.betruorganics.com
About Isodiol International Inc.
Isodiol International Inc. is the market leader in pharmaceutical grade phytochemical compounds and the industry leader in the manufacturing and development of phytoceutical consumer products.
Isodiol is the pioneer of many firsts for the cannabis industry including commercialization of 99%+ pure, bioactive pharmaceutical grade cannabinoids, micro-encapsulations, and nanotechnology for the highest quality consumable and topical skin care products.
Isodiol’s growth strategy includes the development of over-the-counter and pharmaceutical drugs, expanding its phytoceutical portfolio and will aggressively continue international expansion into Latin America, Asia and Europe.
Join Us On Facebook: https://www.facebook.com/isodiol/
Twitter:@isodiol
ON BEHALF OF THE BOARD
Marcos Agramont, CEO & Director
INVESTOR RELATIONS:
Ir@isodiol.com
www.isodiol.com
MEDIA CONTACT:
Carrie Booze
North 6th Agency
212-334-9753 ext.142
Isodiol@n6a.com
Forward-Looking Information:This news release contains “forward-looking information” within the meaning of applicable securities laws relating to statements regarding the Company’s business, products and future of the Company’s business, its product offerings and plans for sales and marketing. Although the Company believes that the expectations reflected in the forward-looking information are reasonable, there can be no assurance that such expectations will prove to be correct. Readers are cautioned to not place undue reliance on forward-looking information. Such forward looking statements are subject to risks and uncertainties that may cause actual results, performance and developments to differ materially from those contemplated by these statements depending on, among other things, the risks that the Company’s products and plan will vary from those stated in this news release and the Company may not be able to carry out its business plans as expected. Except as required by law, the Company expressly disclaims any obligation, and does not intend, to update any forward-looking statements or forward-looking information in this news release. Although the Company believes that the expectations reflected in the forward-looking information are reasonable, there can be no assurance that such expectations will prove to be correct and makes no reference to profitability based on sales reported. The statements in this news release are made as of the date of this release.
The CSE has not reviewed, approved or disapproved the content of this press release.
Click here to connect with Isodiol International Inc. (CSE:ISOL) to receive an Investor Presentation

Source: globenewswire.com


NeutriSci International Inc. (TSXV:NU) (OTCQB: NRXCF) (FSE: 1N9) (the “Company” or “NeutriSci”), the innovator and pioneer behind neuenergy®, is pleased to announce it has entered into a major R&D Memorandum of Understanding with Scientus Pharma Inc. (“Scientus Pharma”). Under the terms of the MOU, both companies have agreed to share their technologies to develop, test, produce, and distribute a medical cannabinoid product for existing retail distribution networks across Canada.
The core ingredients in NeutriSci’s products have significant anti-oxidant properties and health benefits. Scientus Pharma will conduct research on Neutrisci’s products and their components in combination with various cannabinoids. Research activities will initially be funded by Neutrisci. Both companies will have rights for further product development and testing, including potentially preclinical and clinical trials, which may be co-funded.
NeutriSci President Mr. Glen Rehman stated, “This Scientus Pharma partnership helps position us at the forefront of developing new and innovative cannabinoid based medical products in Canada. Scientus Pharma, along with its existing partnerships, is sure to be a dominant player in the cannabis space in Canada. Through a collaborative effort, we will incorporate NeutriSci’s IP, technology and ingredients with Scientus’ expertise, proprietary technical know-how, and resources. By leveraging both parties existing partnerships, we will be positioned to offer the national retail consumer a safe, effective, dose controlled product that completes our ‘plant to blood stream’ strategy.”
“Neutrisci brings a wealth of retail distribution and consumer branding expertise,” said Scientus Chairman Mr. Har Grover. “They have had success innovating with neuenergy and the brand has good presence in several health and wellness settings. Pterostilbene and related compounds present interesting targets for further research and we are looking forward to this collaboration.”
About Scientus Pharma
Hydrx Farms Ltd. O/A Scientus Pharma is a vertically-integrated biopharmaceutical Licensed Dealer under the Narcotics Control Regulations promulgated under the Controlled Drugs and Substances Act (Canada) with a focus on developing and commercializing pharmaceutical-grade medicinal cannabinoid derivative products. Being one of a limited number of Licensed Dealers in Canada authorized to handle cannabinoid products, Scientus Pharma has the ability to wholesale, buy, process and sell cannabinoid derivatives from and to Licensed Producers, as well as international markets. The company recently received its Access to Cannabis for Medical Purposes Regulations (“ACMPR”) license from Health Canada.
www.scientuspharma.com
About NeutriSci International Inc.
NeutriSci specializes in the innovation, production and formulation of nutraceutical products. Established in 2009, NeutriSci is currently focussed on increasing the size of its existing national retail network in Canada by building sustainable sales models with Convenience, Chain Drug, Mass Market and Supermarket retailers for neuenergy® and new novel ingredients for product distribution. It also continues to develop emerging sales channels in the US, Europe and Asia.
www.neutrisci.com
On Behalf of the Board of Directors of
NEUTRISCI INTERNATIONAL INC.
Glen Rehman
CEO & President
Tel: (403) 264-6320
Email: grehman@neutrisci.com
Neuenergy® contains a unique patented combination of blueberries (pterostilbene) and naturally derived caffeine, and is a revolutionary energy tab designed to deliver enhanced focus and mental clarity with no sugar, no calories and no crash associated with typical energy products. To find out more about neuenergy®, please visit www.getneuenergy.com.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.
This news release may include forwardlooking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forwardlooking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forwardlooking statements. Factors that could cause actual results to differ materially from those in forwardlooking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forwardlooking statements except as required under the applicable laws.
Statements in this press release have not been evaluated by the Food and Drug Administration.  Products or ingredients are not intended to diagnose, treat, cure or prevent any disease.
Click here to connect with NeutriSci International Inc. (TSXV:NU)  to receive an Investor Presentation

Source: www.newsfilecorp.com